Evidence map›Paper›PMID 29045138›Full record

ArticleBiochemistry2017

Importance of the C-Terminus of Aldehyde Dehydrogenase 7A1 for Oligomerization and Catalytic Activity.

David A Korasick, Jesse W Wyatt, Min Luo, Adrian R Laciak, Kasi Ruddraraju, Kent S Gates, Michael T Henzl, John J Tanner

Abstract read
In one paragraph

Article in Biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. NADFEBS letters · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David A KorasickDepartment of Biochemistry, University of Missouri , Columbia, Missouri 65211, United States.ORCID 0000-0002-6337-2085
Jesse W WyattDepartment of Chemistry, University of Missouri , Columbia, Missouri 65211, United States.
Min LuoDepartment of Chemistry, University of Missouri , Columbia, Missouri 65211, United States.
Adrian R LaciakDepartment of Chemistry, University of Missouri , Columbia, Missouri 65211, United States.
Kasi RuddrarajuDepartment of Chemistry, University of Missouri , Columbia, Missouri 65211, United States.
Kent S GatesDepartment of Biochemistry, University of Missouri , Columbia, Missouri 65211, United States.ORCID 0000-0002-4218-7411
Michael T HenzlDepartment of Biochemistry, University of Missouri , Columbia, Missouri 65211, United States.
John J TannerDepartment of Biochemistry, University of Missouri , Columbia, Missouri 65211, United States.ORCID 0000-0001-8314-113X
University of Missouri · US

Funding

Integrated Prediction of Protein Struture at 1D, 2D and 3D LevelsR01GM093123 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHENG, JIANLIN · 2010 to 2023
$3.8M
MINOS (Macromolecular Insights on Nucleic acids Optimized by Scattering)R01GM105404 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI TAINER, JOHN A. · 2012 to 2015
$2.1M
NIGMS NIH HHS R01 GM093123NIGMS NIH HHS R01 GM105404
6 · The paper itself

Abstract

Aldehyde dehydrogenase 7A1 (ALDH7A1) catalyzes the terminal step of lysine catabolism, the NAD

Indexed as

Biocatalysis2-Aminoadipic AcidAldehyde DehydrogenaseEpilepsyHumansKineticsLysineProtein MultimerizationProtein Structure, QuaternarySubstrate Specificity2-Aminoadipic AcidAldehyde DehydrogenaseLysine

Identifiers

PMID29045138
PMCPMC5928510
OpenAlexW2766130549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.