Evidence map›Paper›PMID 29044937›Full record

ArticleAddiction biology2018

Selective inhibition of M

Barak W Gunter, Robert W Gould, Michael Bubser, Kevin M McGowan, Craig W Lindsley, Carrie K Jones

Abstract read
In one paragraph

Article in Addiction biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  13. Review
  14. Crystal structure of the MProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  15. Review
  16. Acute Negative Allosteric Modulation of MACS chemical neuroscience · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Barak W GunterDepartment of Pharmacology, Vanderbilt University, Nashville, TN, USA.
Robert W GouldDepartment of Pharmacology, Vanderbilt University, Nashville, TN, USA.
Michael BubserDepartment of Pharmacology, Vanderbilt University, Nashville, TN, USA.
Kevin M McGowanDepartment of Chemistry, Vanderbilt University, Nashville, TN, USA.
Craig W LindsleyDepartment of Pharmacology, Vanderbilt University, Nashville, TN, USA.
Carrie K JonesDepartment of Pharmacology, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0002-1287-9839
Vanderbilt University · US

Funding

Discovery of mAChR5 Modulators for Use in Rodent Models of Drug AddictionR01DA037207 · NIDA · VANDERBILT UNIVERSITY · PI JONES, CARRIE KIMBERLY, LINDSLEY, CRAIG · 2015 to 2017
$1.1M
NIDA NIH HHS R01 DA037207
6 · The paper itself

Abstract

Cocaine use disorder (CUD) remains a debilitating health problem in the United States for which there are no Food and Drug Administration-approved treatment options. Accumulating anatomical and electrophysiological evidence indicates that the muscarinic acetylcholine receptor (mAChR) subtype 5 (M

Indexed as

AnimalsBehavior, AnimalCocaineCocaine-Related DisordersConditioning, OperantDisease Models, AnimalDopamine Uptake InhibitorsDose-Response Relationship, DrugMaleMiceRatsRats, Sprague-DawleyReceptor, Muscarinic M5Reinforcement ScheduleRewardSelf AdministrationCocaineDopamine Uptake InhibitorsReceptor, Muscarinic M5cocaine self-administrationmuscarinic receptornegative allosteric modulation

Identifiers

PMID29044937
PMCPMC5906200
OpenAlexW2765901753

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.