Evidence map›Paper›PMID 29044537›Full record

ArticleThe Laryngoscope2018

In vivo imaging of the internal nasal valve during different conditions using optical coherence tomography.

Anna S Englhard, Maximilian Wiedmann, Georg J Ledderose, Bryan Lemieux, Alan Badran, Joseph C Jing, Zhongping Chen, Veronika Volgger, Brian J F Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Anna S EnglhardDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany.ORCID 0000-0002-1258-6964
Maximilian WiedmannDepartment of Biomedical Engineering, University of California, Irvine, Orange, California, U.S.A.
Georg J LedderoseDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany.ORCID 0000-0002-8451-6498
Bryan LemieuxBeckman Laser Institute, University of California, Irvine, Orange, California, U.S.A.
Alan BadranBeckman Laser Institute, University of California, Irvine, Orange, California, U.S.A.
Joseph C JingDepartment of Biomedical Engineering, University of California, Irvine, Orange, California, U.S.A.
Zhongping ChenDepartment of Biomedical Engineering, University of California, Irvine, Orange, California, U.S.A.
Veronika VolggerDepartment of Otolaryngology-Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany.
Brian J F WongBeckman Laser Institute, University of California, Irvine, Orange, California, U.S.A.
University of California, Irvine · USLudwig-Maximilians-Universität München · DE

Funding

Modeling the Pediatric Upper Airway using A-OCT and Computational Fluid DynamicsR01HL105215 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ELGHOBASHI, SAID E. · 2010 to 2013
$3.7M
Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCTR01HL103764 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WONG, BRIAN · 2010 to 2014
$3.1M
HIGH SPEED HIGH RESOLUTION PHASE RESOLVED OCT/ODTR01EB000293 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING · 2002 to 2009
$1.9M
NHLBI NIH HHS R01 HL103764NHLBI NIH HHS R01 HL105215NIBIB NIH HHS R01 EB000293
6 · The paper itself

Abstract

objectivePreviously, we proposed long-range optical coherence tomography (LR-OCT) to be an effective method for the quantitative evaluation of the nasal valve geometry. Here, the objective was to quantify the reduction in the internal nasal valve angle and cross-sectional area that results in subjective nasal airway obstruction and to evaluate the dynamic behavior of the valve during respiration using LR-OCT.

methodsFor 16 healthy individuals, LR-OCT was performed in each naris during: 1) normal respiration, 2) peak forced inspiration, 3) lateral nasal wall depression (to the onset of obstructive symptoms), and 4) after application of a topical decongestant. The angle and the cross-sectional area of the valve were measured.

resultsA reduction of the valve angle from 18.3° to 14.1° (11° in Caucasians and 17° in Asians) and a decrease of the cross-sectional area from 0.65 cm

conclusionLR-OCT proved to be a fast and readily performed method for the evaluation of the dynamic behavior of the nasal valve. The values of the angle and the cross-sectional area of the valve were reproducible, and changes in size could be accurately delineated. LEVEL OF EVIDENCE: 2b. Laryngoscope, 128:E105-E110, 2018.

Indexed as

AdultFemaleHealthy VolunteersHumansMaleNasal DecongestantsNasal ObstructionNoseRespirationTomography, Optical CoherenceNasal Decongestantsendoscopyinternal nasal valvelong-range Fourier-domainnasal obstructionOptical coherence tomography

Identifiers

PMID29044537
PMCPMC5814348
OpenAlexW2766175265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.