Evidence map›Paper›PMID 29044463›Full record

ArticleJournal of the American Geriatrics Society2017

Prehospital Delay in Older Adults with Acute Myocardial Infarction: The ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction Study.

Gregory M Ouellet, Mary Geda, Terrence E Murphy, Sui Tsang, Mary E Tinetti, Sarwat I Chaudhry

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gregory M OuelletSection of Geriatrics, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.ORCID http://orcid.org/0000-0002-7731-2104
Mary GedaSection of Geriatrics, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Terrence E MurphySection of Geriatrics, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Sui TsangSection of Geriatrics, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Mary E TinettiSection of Geriatrics, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.
Sarwat I ChaudhrySection of General Internal Medicine, Department of Medicine, School of Medicine, Yale University, New Haven, Connecticut.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Risk Stratification in Older Persons with Acute Myocardial Infarction: SILVER-AMIR01HL115295 · NHLBI · YALE UNIVERSITY · PI CHAUDHRY, SARWAT I · 2012 to 2016
$11.3M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL115295NIA NIH HHS P30 AG021342NIA NIH HHS T32 AG019134
6 · The paper itself

Abstract

BACKGROUND/

objectivesTimely administration of antiischemic therapies improves outcomes in individuals with acute myocardial infarction (AMI). Prior literature on delays in AMI care has largely focused on in-hospital delay ("door to balloon" time). Our objective was to identify factors associated with prehospital delay in a contemporary national cohort of older adults with AMI.

designCross-sectional analysis of data from the ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction (SILVER-AMI) study, an observational study of older adults hospitalized for AMI.

settingU.S. academic and community hospitals (N = 94).

participantsIndividuals aged 75 and older hospitalized for AMI (N = 2,500). MEASUREMENTS: Prehospital delay was defined as symptom duration of 6 hours or longer before hospital presentation and was obtained according to participant or caregiver report during AMI hospitalization. Potential predictors of delay from demographic, clinical presentation, comorbid conditions, function, and social support domains were obtained through in-person assessment during the index hospitalization and medical record abstraction.

resultsNonwhite race (adjusted odds ratio (aOR) = 1.54, P = .002), atypical symptoms (aOR = 1.41, P = .001), and heart failure (HF) (aOR = 1.35, P = .006 for HF) were significantly associated with delay.

conclusionIn contrast with younger AMI populations, female sex and diabetes mellitus were not associated with delay in this older cohort, but factors from other domains (nonwhite race, atypical symptoms, and HF) were significantly associated with delay. These results can be used to customize future public health efforts to encourage early presentation for older adults with AMI.

Indexed as

Acute DiseaseAgedAged, 80 and overAge FactorsComorbidityDelayed DiagnosisEmergency Medical ServicesFemaleHospitalizationHumansMaleMyocardial InfarctionPatient AdmissionSex Factorsmyocardial infarctionprehospital delayrisk factors

Identifiers

PMID29044463
PMCPMC5681402

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.