Evidence map›Paper›PMID 29044125›Full record

ArticleScientific reports2017

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

Shan Li, Amy Teegarden, Emily M Bauer, Jaewoo Choi, Nadia Messaddeq, David A Hendrix, Gitali Ganguli-Indra, Mark Leid, Arup K Indra

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. BCL11A Expression in Breast Cancer.Current issues in molecular biology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shan LiDepartment of Pharmaceutical Sciences, College of Pharmacy, OSU, Corvallis, Oregon, 97331, USA.
Amy TeegardenDepartment of Biochemistry and Biophysics, OSU, Corvallis, Oregon, 97331, USA.
Emily M BauerDepartment of Pharmaceutical Sciences, College of Pharmacy, OSU, Corvallis, Oregon, 97331, USA.
Jaewoo ChoiLinus Pauling Science Center, OSU, Corvallis, Oregon, 97331, USA.
Nadia MessaddeqInstitut de Génétique et de Biologie Moléculaire et Cellulaire, Department of Functional Genomics, Inserm U596 and CNRS UMR 7104, Illkirch-Graffenstaden, 67400, France.
David A HendrixDepartment of Biochemistry and Biophysics, OSU, Corvallis, Oregon, 97331, USA.
Gitali Ganguli-IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, OSU, Corvallis, Oregon, 97331, USA.
Mark LeidDepartment of Pharmaceutical Sciences, College of Pharmacy, OSU, Corvallis, Oregon, 97331, USA.
Arup K IndraDepartment of Pharmaceutical Sciences, College of Pharmacy, OSU, Corvallis, Oregon, 97331, USA. arup.indra@oregonstate.edu.ORCID 0000-0001-6137-7555
Oregon State University · USCentre National de la Recherche Scientifique · FR

Funding

Triple Quadrupole/Linear Ion Trap LC-MS/MS for LPIS10RR027878 · NCRR · OREGON STATE UNIVERSITY · PI STEVENS, JAN FREDERIK · 2010 to 2010
$484k
6 · The paper itself

Abstract

The epidermal permeability barrier (EPB) prevents organisms from dehydration and infection. The transcriptional regulation of EPB development is poorly understood. We demonstrate here that transcription factor COUP-TF-interacting protein 1 (CTIP1/BCL11A; hereafter CTIP1) is highly expressed in the developing murine epidermis. Germline deletion of Ctip1 (Ctip1

Indexed as

Cell DifferentiationLipid MetabolismAcetyltransferasesAnimalsCarrier ProteinsDNA-Binding ProteinsEpidermal CellsFatty Acid ElongasesFos-Related Antigen-2Gene Expression Regulation, DevelopmentalMiceMice, Inbred C57BLNuclear ProteinsRepressor ProteinsSkinAcetyltransferasesBcl11a protein, mouseCarrier ProteinsDNA-Binding ProteinsFatty Acid ElongasesFosl2 protein, mouseFos-Related Antigen-2Nuclear ProteinsRepressor Proteins

Identifiers

PMID29044125
PMCPMC5647389
OpenAlexW2762561848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.