Evidence map›Paper›PMID 29044062›Full record

ArticleIndian journal of ophthalmology2017

Changing epidemiology of neovascular glaucoma from 2002 to 2012 at King Khaled Eye Specialist Hospital, Saudi Arabia.

Abdullah Al-Bahlal, Rajiv Khandekar, Khalid Al Rubaie, Tariq Alzahim, Deepak P Edward, Igor Kozak

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Profile of newly referred glaucoma patients to the largest tertiary eye care hospital in Saudi Arabia.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Abdullah Al-BahlalDepartment of Glaucoma, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Rajiv KhandekarDepartment of Research, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Khalid Al RubaieDepartment of Glaucoma, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Tariq AlzahimDepartment of Glaucoma, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Deepak P EdwardDepartment of Glaucoma, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore Maryland, USA.
Igor KozakDepartment of Glaucoma, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
King Khaled Eye Specialist Hospital · SAJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim is to present the incidence and determinants of neovascular glaucoma (NVG) in Saudi Arabia.

methodsA retrospective review of NVG cases (2002-2012) was included to estimate the incidence. The determinants included gender, age, comorbidities, lens status, type of NVG, and visual acuity on presentation. The impact of antiangiogenic therapy on NVG incidence was studied.

resultsWe studied 597 eyes with NVG. The incidence was 6.6/10,000. It declined from 13/10,000 in 2008-0.1/10,000 in 2012 (P < 0.001). The decline in 2008 coincided with the introduction of intravitreal injection bevacizumab in Saudi Arabia. Males had a significantly higher NVG risk (odds ratio [OR] = 2.2). Diabetes and hypertension were associated with NVG in 88% and 42.7% of cases, respectively. In 377 (72%) diabetic patients, the glycemic control was poor (HbA1C >7%). Visual acuity was 20/20-20/40 in 14 (2%), 20/50-20/200 in 79 (13%), 20/200-20/400 in 456 (76%), and <20/400 in 45 (7%) eyes. Intraocular pressure was higher than 30 mmHg in 438 (73%) eyes. The cup-to-disc (CD) ratio was >0.8 in 86 (14%) eyes. During the early period (2002-2007) and later period (2008-2012), CD ratio (χ2 = 4, P = 0.09) and anterior chamber angle (P = 0.8) were not different. The presence of NVG in contralateral eye (OR = 0.8, P = 0.3) in both periods was similar.

conclusionsNVG was associated with diabetes in a very large proportion of patients. It was significantly associated with males, and with poor glycemic control and poor vision at presentation. The incidence of NVG declined after the introduction of intravitreal bevacizumab.

Indexed as

Intraocular PressureVisual AcuityAdolescentAdultAgedAged, 80 and overAge DistributionChildFemaleGlaucoma, NeovascularHospitals, SpecialHumansIncidenceMaleMiddle AgedRetrospective Studies

Identifiers

PMID29044062
PMCPMC5678333
OpenAlexW2766749739

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.