Evidence map›Paper›PMID 29043547›Full record

ArticleObesity surgery2018

Age-Related Effects of Bariatric Surgery on Early Atherosclerosis and Cardiovascular Risk Reduction.

Frederik H W Jonker, Vera A A van Houten, Leontine H Wijngaarden, René A Klaassen, André A E A de Smet, André Niezen, Lodewijk J D M Schelfhout, Tobias A Bruning, Erwin van der Harst

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Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Frederik H W JonkerDepartment of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, Netherlands. jonkerfrederik@hotmail.com.
Vera A A van HoutenDepartment of Surgery, Groene Hart Hospital, Gouda, Netherlands.
Leontine H WijngaardenDepartment of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, Netherlands.
René A KlaassenDepartment of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, Netherlands.
André A E A de SmetDepartment of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, Netherlands.
André NiezenDepartment of Radiology and Nuclear Medicine, Maasstad Hospital, Rotterdam, Netherlands.
Lodewijk J D M SchelfhoutDepartment of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands.
Tobias A BruningDepartment of Cardiology, Maasstad Hospital, Rotterdam, Netherlands.
Erwin van der HarstDepartment of Surgery, Maasstad Hospital, Maasstadweg 21, 3079 DZ, Rotterdam, Netherlands.
Maasstad Ziekenhuis · NLGroene Hart Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarotid intima-media thickness (CIMT) is increasingly used as a prognostic indicator for early atherosclerosis and the development of cardiovascular disease. The objective of this study is to assess the exact effects of bariatric surgery on CIMT reduction in different age groups.

methodsCIMT was measured just proximal to the bifurcation of the carotid artery in 166 patients with mean body mass index of 43.4 kg/m

resultsMedian follow-up was 12 months; 12% were lost to follow-up. Mean CIMT values at 12 months after bariatric surgery were significantly lower compared to baseline (0.619 vs. 0.587 mm, p = 0.005 in women and 0.675 vs. 0.622 mm, p = 0.037 in men, respectively), and these effects were statistically significant in all age groups. The mean reduction of CIMT for patients < 50 years at 12 months was 0.043 mm (- 7.0%), while CIMT was reduced with 0.013 mm for patients ≥ 50 years (- 1.9%, p = 0.022). At 12 months after bariatric surgery, FRS had decreased with 52% in patients < 50 years as compared with 35% in patients ≥ 50 years (p = 0.025).

conclusionsBariatric surgery resulted in a significant CIMT decrease in patients with morbid obesity in all evaluated age categories. These beneficial effects of bariatric surgery were more pronounced in younger patients, while cardiovascular risk reduction by bariatric surgery appeared inferior in patients of 50 years and older.

Indexed as

Bariatric SurgeryAdultAge FactorsAtherosclerosisBody Mass IndexCardiovascular DiseasesCarotid ArteriesCarotid Intima-Media ThicknessFemaleHumansMaleMiddle AgedObesity, MorbidPrognosisRisk FactorsRisk Reduction BehaviorAgeAtherosclerosisBariatric surgeryCarotid intima-media thickness

Identifiers

PMID29043547
OpenAlexW2766249784

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.