Evidence map›Paper›PMID 29042764›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2017

The association between objectively measured physical activity and morning symptoms in COPD.

Amanda R van Buul, Marise J Kasteleyn, Niels H Chavannes, Christian Taube

Abstract readObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. The Relationship Between Morning Symptoms and the Risk of Future Exacerbations in COPD.International journal of chronic obstructive pulmonary disease · 2020
    Article
  6. Observational
  7. Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amanda R van BuulDepartment of Pulmonology.
Marise J KasteleynDepartment of Pulmonology.
Niels H ChavannesDepartment of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands.
Christian TaubeDepartment of Pulmonology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe morning is the most bothersome period for COPD patients. Morning symptom severities in different Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages are not well studied. Furthermore, factors that are associated with morning symptoms, especially the associations with objectively measured physical activity, are also not well described. MATERIALS AND

methodsThe aim of this cross-sectional observational study was to assess morning symptom severity in GOLD A, B, C and D patients, according to the definitions of the GOLD 2015 statement. Morning symptoms were assessed with the PRO-Morning COPD Symptoms Questionnaire. Differences in morning symptom severity between different COPD stages were assessed with a one-way analysis of variance followed by post hoc analyses. The association between dyspnea severity (assessed with the modified Medical Research Council scale), health status, airflow limitation, lung hyperinflation, anxiety and depression, inflammatory parameters, exacerbations, objectively measured physical activity parameters retrieved from accelerometry and morning symptom severity was evaluated using linear regression analysis.

resultsEighty patients were included (aged 65.6±8.7 years, forced expiratory volume in 1 second [FEV

conclusionPatients with overall more symptomatic COPD have significant higher morning symptom scores. Morning symptom severity was associated with important clinical outcomes: lower health status, more symptoms, increased anxiety and depression, fewer steps a day, less time in moderate and vigorous physical activity with bouts of at least 10 minutes and lower FEV

Indexed as

Circadian RhythmExerciseActigraphyAgedCross-Sectional StudiesDyspneaFemaleForced Expiratory VolumeHumansLinear ModelsLungMaleMiddle AgedPatient Reported Outcome MeasuresPredictive Value of TestsPulmonary Disease, Chronic Obstructiveaccelerometrychronic obstructive pulmonary diseasemorning symptomsphysical activityPRO-Morning COPD Symptoms Questionnaire

Identifiers

PMID29042764
PMCPMC5633288

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.