ReviewNature reviews. Neuroscience2017
Motor cortex - to act or not to act?
Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
84 citing papers in PubMed, 2 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Visuospatial and Visuomotor Abilities of Individuals with Neurofibromatosis Type 1: A Systematic Review and Meta-analysis.Neuropsychology review · 2026Pooled it
- Transcranial ultrasound stimulation parameters for neurological diseases: a systematic review.Frontiers in neurology · 2025Pooled it
- NLX-112, a Selective 5-HT1A Receptor Agonist, Upregulates GDNF and is Neuroprotective Against MPTP-Induced Nigrostriatal Degeneration in a Mouse Model of Parkinson's Disease.ACS chemical neuroscience · 2026Article
- Inferring brain-wide interactions using data-constrained recurrent neural network models.Neuron · 2026Article
- Linking temporal dynamics of children's natural behavior to brain development.Developmental cognitive neuroscience · 2026Article
- Motor Cortex VIP Interneurons Participate in Dexmedetomidine-Associated Sleep Modulation.Molecular neurobiology · 2026Article
- Spatial connectivity for local cortical homogeneity.Research square · 2026Article
- Binding and retrieval of omitted responses in complex response sequences.Attention, perception & psychophysics · 2026Article
- Prediction, syntax and semantic grounding in the brain and large language models.Scientific reports · 2026Article
- Article
- The frequency-dependent effects of primary hand motor cortex stimulation on volitional finger movement.Clinical neurophysiology practice · 2026Article
- Spacetime concordance in the primate cortex.bioRxiv : the preprint server for biology · 2025Article
- Descending projection neurons in the primary sensorimotor cortex regulate neuropathic pain and locomotion in mice.Nature communications · 2025Article
- Multiple cortical systems influence a single vibrissa muscle.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Repeated Sprint Performance and Inter-Limb Asymmetry in Elite Female Sprinters: A Study of Lactate Dynamics and Lower Limb Muscle Activity.Journal of functional morphology and kinesiology · 2025Article
- Decoupling of motor cortex to movement in Parkinson's dyskinesia rescued by sub-anaesthetic ketamine.Brain : a journal of neurology · 2025Article
- Whether or not to act is determined by distinct signals from motor thalamus and orbitofrontal cortex to secondary motor cortex.Nature communications · 2025Article
- Cortical areas associated to higher cognition drove primate brain evolution.Communications biology · 2025Article
- Role and modulation of various spinal pathways for human upper limb control in different gravity conditions.PLoS computational biology · 2025Article
- Potential impacts of acupuncture on motor function recovery after ischemic stroke: insights from basic and clinical studies.Frontiers in cellular neuroscience · 2025Review
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The motor cortex is a large frontal structure in the cerebral cortex of eutherian mammals. A vast array of evidence implicates the motor cortex in the volitional control of motor output, but how does the motor cortex exert this 'control'? Historically, ideas regarding motor cortex function have been shaped by the discovery of cortical 'motor maps' - that is, ordered representations of stimulation-evoked movements in anaesthetized animals. Volitional control, however, entails the initiation of movements and the ability to suppress undesired movements. In this article, we highlight classic and recent findings that emphasize that motor cortex neurons have a role in both processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.