ArticleScientific reports2017
Sedum alfredii SaNramp6 Metal Transporter Contributes to Cadmium Accumulation in Transgenic Arabidopsis thaliana.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 98 citations in OpenAlex.
- Molecular mechanisms of cadmium uptake in Amanita muscaria: the role of AmNRAMP1.Folia microbiologica · 2026Article
- Screening and expression analysis of the NRAMP gene family in Kiwifruit under cadmium stress reveals the potential role of AcNRAMP7.BMC plant biology · 2025Article
- Selenium Alleviates Cadmium Toxicity by Regulating Carbon Metabolism, AsA-GSH Cycle, and Cadmium Transport inPlants (Basel, Switzerland) · 2025Article
- Differentiation and response mechanisms of the endophytic flora of plants ecologically restored in the ilmenite area.Frontiers in microbiology · 2025Article
- Zinc Enhances Cadmium Accumulation in Shoots of HyperaccumulatorPlants (Basel, Switzerland) · 2024Article
- The Uptake, Transfer, and Detoxification of Cadmium in Plants and Its Exogenous Effects.Cells · 2024Review
- SpSIZ1 from hyperaccumulatorFrontiers in plant science · 2024Article
- Article
- Significance and genetic control of membrane transporters to improve phytoremediation and biofortification processes.Molecular biology reports · 2023Review
- Bacterial Communities Associated with the Roots ofMicroorganisms · 2023Review
- The Potential of CRISPR/Cas Technology to Enhance Crop Performance on Adverse Soil Conditions.Plants (Basel, Switzerland) · 2023Review
- Transcriptional Regulatory Network of Plant Cadmium Stress Response.International journal of molecular sciences · 2023Review
- Downregulated expression ofPhotosynthetica · 2023Article
- A novel geneFrontiers in plant science · 2023Article
- Advances in Genes-Encoding Transporters for Cadmium Uptake, Translocation, and Accumulation in Plants.Toxics · 2022Review
- PcNRAMP1 Enhances Cadmium Uptake and Accumulation inInternational journal of molecular sciences · 2022Article
- Genetic system underlying responses of Cryptococcus neoformans to cadmium.Current genetics · 2022Article
- Identification and Analysis of bZIP Family Genes inFrontiers in plant science · 2022Article
- Transcriptome analysis of the response ofFrontiers in microbiology · 2022Article
- The Role of Membrane Transporters in Plant Growth and Development, and Abiotic Stress Tolerance.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The plant natural resistance-associated macrophage protein (Nramp) family plays an important role in tolerance to heavy metal stress. However, few Nramps have been functionally characterized in the heavy metal-accumulating plant Sedum alfredii. Here, Nramp6 was cloned and identified from S. alfredii and its function analyzed in transgenic Arabidopsis thaliana. SaNramp6 cDNA contains an open reading frame of 1, 638 bp encoding 545 amino acids. SaNramp6's expression can be induced by cadmium (Cd) stress, and, after treatment, it peaked at one week and 12 h in the roots and leaves, respectively. SaNramp6 localized to the plasma membrane in protoplasts isolated from A. thaliana, Nicotiana benthamiana lower leaf and onion (Allium cepa) epidermal cells. The heterologous expression of SaNramp6 in the Δycf1 yeast mutant increased the Cd content in yeast cells. SaNramp6 also rescued the low Cd accumulation of the A. thaliana nramp1 mutant. Transgenic A. thaliana expressing SaNramp6 exhibited high Cd accumulation levels, as determined by a statistical analysis of the Cd concentration, translocation factors and net Cd
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.