Evidence map›Paper›PMID 29042594›Full record

ArticleScientific reports2017

Serum SAA1 and APOE are novel indicators for human cytomegalovirus infection.

Ni Xie, Zhonghang Li, Ran Zuo, Suwen Qi, Ting Zhu, Litao Liu, Lili Wan, Jianhui Yuan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Nanotechnology Frontiers in γ-Herpesviruses Treatments.International journal of molecular sciences · 2021
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ni XieInstitute of Translation Medicine, Shenzhen Second People's Hospital, Sungang West Road, Shenzhen, 518000, China.
Zhonghang LiCollege of Life Sciences, Shenzhen University, Nanhai Ave 3688, Shenzhen, 518060, China.
Ran ZuoInstitute of Toxicology, Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China.
Suwen QiCollege of Life Sciences, Shenzhen University, Nanhai Ave 3688, Shenzhen, 518060, China.
Ting ZhuInstitute of Translation Medicine, Shenzhen Second People's Hospital, Sungang West Road, Shenzhen, 518000, China.
Litao LiuInstitute of Translation Medicine, Shenzhen Second People's Hospital, Sungang West Road, Shenzhen, 518000, China.
Lili WanInstitute of Translation Medicine, Shenzhen Second People's Hospital, Sungang West Road, Shenzhen, 518000, China.
Jianhui YuanInstitute of Toxicology, Shenzhen Center for Disease Control and Prevention, No 8 Longyuan Road, Nanshan District, Shenzhen, 518055, China. jianhui_yuan@126.com.
Shenzhen Second People's Hospital · CNShenzhen Center for Disease Control and Prevention · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) infection is a global concern and highly infectious. HCMV-infected individuals are often carriers with damaged immunity. However few diagnostic indicators block HMCV control and prevention. Thus, we measured 21 serum proteins related to HCMV infection using iTRAQ-labeling based quantitative proteomic approaches and SAA1 and APOE were confirmed as candidate serum indicators for identification of HMCV infection according to ROC curve analysis and that co-occurrence of SAA1 and APOE are better markers than individual proteins.

Indexed as

CytomegalovirusApolipoproteins EBiomarkersBlood ProteinsChromatography, LiquidCytomegalovirus InfectionsHumansMass SpectrometryPeptidesProteomeProteomicsROC CurveSerum Amyloid A ProteinApolipoproteins EBiomarkersBlood ProteinsPeptidesProteomeSAA1 protein, humanSerum Amyloid A Protein

Identifiers

PMID29042594
PMCPMC5645357
OpenAlexW2762532708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.