Evidence map›Paper›PMID 29042535›Full record

ArticleNature communications2017

Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.

Olga Rechkoblit, Alexander Kolbanovskiy, Hannah Landes, Nicholas E Geacintov, Aneel K Aggarwal

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Making Choices: DNA Replication Fork Recovery Mechanisms.Seminars in cell & developmental biology · 2021
    Review
  4. Article
  5. Article
  6. Visualizing Rev1 catalyze protein-template DNA synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Article
  8. Review
  9. Structure and function relationships in mammalian DNA polymerases.Cellular and molecular life sciences : CMLS · 2020
    Review
  10. Lsm12 Mediates Deubiquitination of DNA Polymerase η To HelpApplied and environmental microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Olga RechkoblitDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Box 1677, 1425 Madison Avenue, New York, NY, 10029, USA. olga.rechkoblit@mssm.edu.ORCID http://orcid.org/0000-0003-4270-7242
Alexander KolbanovskiyDepartment of Chemistry, New York University, 31 Washington Place, New York, NY, 10003-5180, USA.
Hannah LandesDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Box 1677, 1425 Madison Avenue, New York, NY, 10029, USA.
Nicholas E GeacintovDepartment of Chemistry, New York University, 31 Washington Place, New York, NY, 10003-5180, USA.
Aneel K AggarwalDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Box 1677, 1425 Madison Avenue, New York, NY, 10029, USA.
Icahn School of Medicine at Mount Sinai · USNew York University · US

Funding

Genetic and molecular mechanisms of replication of araC damaged DNAR01CA200575 · NCI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, SATYA · 2016 to 2020
$2.0M
Recognition of Environmental Carcinogen-DNA lesions by NER ProteinsR01ES024050 · NIEHS · NEW YORK UNIVERSITY · PI GEACINTOV, NICHOLAS E · 2014 to 2018
$1.8M
NCI NIH HHS R01 CA200575NIEHS NIH HHS R01 ES024050
6 · The paper itself

Abstract

Benzo[a]pyrene (BP) is a carcinogen in cigarette smoke which, after metabolic activation, can react with the exocyclic N

Indexed as

Benzo(a)pyreneCatalytic DomainCrystallography, X-RayDNA AdductsDNA RepairDNA ReplicationGuanineMetalsNucleotidyltransferasesOligonucleotidesProtein ConformationSaccharomyces cerevisiae ProteinsStereoisomerismY-Family DNA PolymerasesBenzo(a)pyreneDNA AdductsGuanineMetalsNucleotidyltransferasesOligonucleotidesREV1 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsY-Family DNA Polymerases

Identifiers

PMID29042535
PMCPMC5645340
OpenAlexW2763535680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.