Evidence map›Paper›PMID 29042531›Full record

ArticleNature communications2017

Extrafollicular CD4

Ruishu Deng, Christian Hurtz, Qingxiao Song, Chanyu Yue, Gang Xiao, Hua Yu, Xiwei Wu, Markus Muschen, Stephen Forman, Paul J Martin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  6. Article
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  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Human Effectors of Acute and Chronic GVHD Overexpress CD83 and Predict Mortality.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Targeting TNature immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Ruishu DengDiabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Christian HurtzDepartment of Laboratory Medicine, University of California, San Francisco, CA, 94143, USA.
Qingxiao SongDiabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Chanyu YueDepartment of Cancer Immunotherapeutic and Tumor Immunology, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Gang XiaoDepartment of Laboratory Medicine, University of California, San Francisco, CA, 94143, USA.
Hua YuDepartment of Cancer Immunotherapeutic and Tumor Immunology, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Xiwei WuDepartment of Molecular and Cellular Biology, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Markus MuschenDepartment of Laboratory Medicine, University of California, San Francisco, CA, 94143, USA.
Stephen FormanHematologic Malignancies and Stem Cell Transplantation Institute, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA.
Paul J MartinFred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, 98109, USA.
Defu ZengDiabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, 91010, USA. dzeng@coh.org.ORCID http://orcid.org/0000-0001-9585-1411
City of Hope · USUniversity of California, San Francisco · USFujian Medical University · CNSanford Burnham Prebys Medical Discovery Institute · USUniversity of Washington · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Metabolic gatekeepers in B-cell malignanciesR35CA197628 · NCI · YALE UNIVERSITY · PI Markus Müschen · 2016 to 2026
$11.7M
Role of autoreactivity in the pathogenesis of chronic GVHDR01AI066008 · NIAID · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI ZENG, DEFU · 2005 to 2020
$6.1M
CD25-mediated feedback control of BCR-signaling and its oncogenic mimicsR01CA213138 · NCI · YALE UNIVERSITY · PI MÜSCHEN, MARKUS · 2017 to 2022
$1.9M
Role of autoreactivity in the pathogenesis of chronic GVHDR56AI066008 · NIAID · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI ZENG, DEFU · 2015 to 2021
$777k
NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA213138NCI NIH HHS R35 CA197628NIAID NIH HHS R01 AI066008NIAID NIH HHS R56 AI066008
6 · The paper itself

Abstract

Chronic graft-versus-host disease (cGVHD) is an autoimmune-like syndrome mediated by pathogenic CD4

Indexed as

AnimalsAutoimmune DiseasesB-LymphocytesCD4-Positive T-LymphocytesChronic DiseaseGerminal CenterGraft vs Host DiseaseHumansMaleMiceMice, Inbred BALB CMice, Inbred C57BLProto-Oncogene Proteins c-bcl-6STAT3 Transcription FactorT-Lymphocytes, Helper-InducerBcl6 protein, mouseProto-Oncogene Proteins c-bcl-6Stat3 protein, mouseSTAT3 Transcription Factor

Identifiers

PMID29042531
PMCPMC5645449
OpenAlexW2763238036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.