ArticleProceedings of the National Academy of Sciences of the United States of America2017
Across the tree of life, radiation resistance is governed by antioxidant Mn
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed.
- DrPitA-mediated enrichment of intracellular manganese and phosphate contributes to oxidative stress resistance ofApplied and environmental microbiology · 2026Article
- Low-Intensity, Short-Duration Proton Irradiation Enhances Oxidative Stress Sensitivity ofJournal of fungi (Basel, Switzerland) · 2026Article
- Stress-Induced Cross-Protection and Combined Stress Responses in Extremotolerant Black Yeasts.Journal of fungi (Basel, Switzerland) · 2026Article
- Elucidating the interplay between intracellular manganese-iron-ratio and radiotolerance across all domains of life.FEMS microbes · 2026Article
- Feeding Drosophila highly radioresistant fungi improves survival and gut morphology following acute gamma radiation exposure.Scientific reports · 2025Article
- Article
- Metal-induced biofilm formation by radiation resistant bacteria Deinococcus radiodurans and Deinococcus indicus.Extremophiles : life under extreme conditions · 2025Article
- The Role of the MntABC Transporter System in the Oxidative Stress Resistance ofInternational journal of molecular sciences · 2025Article
- Efficient Production of Reactive Oxidants by Atmospheric Bacterial-Derived Organic Matter in the Aqueous Phase.Environmental science & technology · 2025Article
- Article
- Prophylactically Feeding Manganese toAntioxidants (Basel, Switzerland) · 2025Article
- Trace Elements in Medicinal Metallomics.Mini reviews in medicinal chemistry · 2025Review
- The ternary complex of MnProceedings of the National Academy of Sciences of the United States of America · 2024Article
- TolRad, a model for predicting radiation tolerance using Pfam annotations, identifies novel radiosensitive bacterial species from reference genomes and MAGs.Microbiology spectrum · 2024Article
- DdrC, a unique DNA repair factor from D. radiodurans, senses and stabilizes DNA breaks through a novel lesion-recognition mechanism.Nucleic acids research · 2024Article
- Black yeasts in hypersaline conditions.Applied microbiology and biotechnology · 2024Review
- Comparative genomics ofFrontiers in microbiology · 2024Article
- Polyextremophile engineering: a review of organisms that push the limits of life.Frontiers in microbiology · 2024Review
- An inorganic mineral-based protocell with prebiotic radiation fitness.Nature communications · 2023Article
- Transcriptomic and genomic effects of gamma-radiation exposure on strains of the black yeastMicrobiology spectrum · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
Despite concerted functional genomic efforts to understand the complex phenotype of ionizing radiation (IR) resistance, a genome sequence cannot predict whether a cell is IR-resistant or not. Instead, we report that absorption-display electron paramagnetic resonance (EPR) spectroscopy of nonirradiated cells is highly diagnostic of IR survival and repair efficiency of DNA double-strand breaks (DSBs) caused by exposure to gamma radiation across archaea, bacteria, and eukaryotes, including fungi and human cells. IR-resistant cells, which are efficient at DSB repair, contain a high cellular content of manganous ions (Mn
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.