Evidence map›Paper›PMID 29042505›Full record

ArticleRNA (New York, N.Y.)2018

Binding synergy as an essential step for tRNA editing and modification enzyme codependence in

Katherine M McKenney, Mary Anne T Rubio, Juan D Alfonzo

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. The life and times of a tRNA.RNA (New York, N.Y.) · 2023
    Review
  3. The RNA methyltransferase METTL8 installs mNature communications · 2022
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katherine M McKenneyDepartment of Microbiology, Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA.
Mary Anne T RubioDepartment of Microbiology, Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA.
Juan D AlfonzoDepartment of Microbiology, Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA.
The Ohio State University · US

Funding

tRNA editing by deamination: Balancing affinity and specifictyR01GM084065 · NIGMS · OHIO STATE UNIVERSITY · PI ALFONZO, JUAN D · 2008 to 2021
$4.0M
NIGMS NIH HHS R01 GM084065
6 · The paper itself

Abstract

Transfer RNAs acquire a variety of naturally occurring chemical modifications during their maturation; these fine-tune their structure and decoding properties in a manner critical for protein synthesis. We recently reported that in the eukaryotic parasite,

Indexed as

KineticsProtein BindingProtozoan ProteinsRNA-Binding ProteinsRNA EditingRNA, ProtozoanRNA, TransferThermodynamicsTrypanosoma brucei bruceiProtozoan ProteinsRNA-Binding ProteinsRNA, ProtozoanRNA, TransfermodificationRNA editingT. bruceitRNA

Identifiers

PMID29042505
PMCPMC5733570
OpenAlexW2766073018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.