Evidence map›Paper›PMID 29042502›Full record

ArticlemBio2017

Lipopolysaccharide from Crypt-Specific Core Microbiota Modulates the Colonic Epithelial Proliferation-to-Differentiation Balance.

Tomoaki Naito, Céline Mulet, Cristina De Castro, Antonio Molinaro, Azadeh Saffarian, Giulia Nigro, Marion Bérard, Mélanie Clerc, Amy B Pedersen, Philippe J Sansonetti and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 109 citations in OpenAlex.

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  16. IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Review
  18. Cancers · 2023
    Review
  19. Association of GILZ with MUC2, TLR2, and TLR4 in Inflammatory Bowel Disease.International journal of molecular sciences · 2023
    Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Tomoaki NaitoUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France.
Céline MuletUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France.
Cristina De CastroDepartment of Agricultural Sciences, Porici (NA), Italy.
Antonio MolinaroDipartimento di Scienze Chimiche, Università di Napoli Federico II, Naples, Italy.
Azadeh SaffarianUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France.
Giulia NigroUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France.
Marion BérardAnimalerie Centrale, Institut Pasteur, Paris, France.
Mélanie ClercSchool of Biological Sciences & Centre for Immunity, Infection and Evolution (CIIE), University of Edinburgh, Edinburgh, United Kingdom.
Amy B PedersenSchool of Biological Sciences & Centre for Immunity, Infection and Evolution (CIIE), University of Edinburgh, Edinburgh, United Kingdom.
Philippe J SansonettiUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France philippe.sansonetti@pasteur.fr.
Thierry PédronUnité de Pathogénie Microbienne Moléculaire, INSERM U1202, Institut Pasteur, Paris, France.
Inserm · FRInstitut Pasteur · FRCentre for Immunity, Infection and Evolution · GBCollège de France · FRUniversity of Edinburgh · GBUniversity of Naples Federico II · IT

Funding

Wellcome TrustWellcome Trust 095831
6 · The paper itself

Abstract

We identified a crypt-specific core microbiota (CSCM) dominated by strictly aerobic, nonfermentative bacteria in murine cecal and proximal colonic (PC) crypts and hypothesized that, among its possible functions, it may affect epithelial regeneration. In the present work, we isolated representative CSCM strains using selective media based upon our initial 16S rRNA-based molecular identification (i.e.,

Indexed as

AnimalsApoptosisCell DifferentiationCell ProliferationCells, CulturedColonEpithelial CellsGastrointestinal MicrobiomeGram-Negative BacteriaIntestinal MucosaLipopolysaccharidesMiceStem CellsLipopolysaccharideshomeostasisintestinal stem cellsLPSnecroptosis

Identifiers

PMID29042502
PMCPMC5646255
OpenAlexW2765353696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.