Evidence map›Paper›PMID 29042497›Full record

ArticlemBio2017

A Single Dual-Function Enzyme Controls the Production of Inflammatory NOD Agonist Peptidoglycan Fragments by

Jonathan D Lenz, Kathleen T Hackett, Joseph P Dillard

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Mutation ofJournal of bacteriology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview.International journal of molecular sciences · 2019
    Review
  15. Infection and immunity · 2019
    Article
  16. Review
  17. Review
  18. Comparative Analysis of Peptidoglycans FromFrontiers in microbiology · 2019
    Article
  19. Selective Inhibition ofAntimicrobial agents and chemotherapy · 2018
    Article
  20. Interplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens.Microbiology and molecular biology reviews : MMBR · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jonathan D LenzDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-2637-9720
Kathleen T HackettDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Joseph P DillardDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA jpdillard@wisc.edu.
University of Wisconsin–Madison · US

Funding

Peptidoglycan metabolism and fragment releaseR01AI097157 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI DILLARD, JOSEPH P · 2012 to 2022
$5.6M
Microbial Pathogenesis &Host Responses Training ProgramT32AI055397 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN · 2003 to 2024
$5.5M
Outer membrane vesicles and peptidoglycan of Neisseria gonorrhoeaeF32AI115911 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI LENZ, JONATHAN DAVID · 2015 to 2016
$112k
NIAID NIH HHS F32 AI115911NIAID NIH HHS R01 AI097157NIAID NIH HHS T32 AI055397
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarboxypeptidasesCell LineHost-Pathogen InteractionsHumansNeisseria gonorrhoeaeNod1 Signaling Adaptor ProteinPeptidoglycanSerine ProteasesCarboxypeptidasesNOD1 protein, humanNod1 Signaling Adaptor ProteinPeptidoglycanSerine Proteaseshigh-pressure liquid chromatographyinnate immunityNeisseria gonorrhoeaepeptidoglycanpeptidoglycan hydrolases

Identifiers

PMID29042497
PMCPMC5646250
OpenAlexW2767055920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.