ArticleNitric oxide : biology and chemistry2017
Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study.
Open access · hybridAbstract read
In one paragraph
Article in Nitric oxide : biology and chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Effects of Dietary Nitrates on Time Trial Performance in Athletes with Different Training Status: Systematic Review.Nutrients · 2020Pooled it
- Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude - A randomised controlled trial (Xtreme Alps).Nitric oxide : biology and chemistry · 2020Trial
- Exploring saliva as a biofluid for biomonitoring of diet-related contaminants exposure: insights from a literature mining approach.Journal of exposure science & environmental epidemiology · 2026Review
- Nutrition, hydration and supplementation considerations for mountaineers in high-altitude conditions: a narrative review.Frontiers in sports and active living · 2024Review
- The Oxygen Cascade from Atmosphere to Mitochondria as a Tool to Understand the (Mal)adaptation to Hypoxia.International journal of molecular sciences · 2023Review
- Post-exposure persistence of nitric oxide upregulation in skin cells irradiated by UV-A.Scientific reports · 2022Article
- Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude - Further Results From the Xtreme Alps Study.Frontiers in physiology · 2022Article
- Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress: Overwintering in Antarctic Concordia Station.Oxidative medicine and cellular longevity · 2022Article
- Article
- Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?Redox biology · 2019Article
- Population History and Altitude-Related Adaptation in the Sherpa.Frontiers in physiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 4 institutions in 1 country.
Andrew F CumpsteyCritical Care Research Area, Southampton NIHR Respiratory Biomedical Research Unit, Tremona Road, Southampton, SO16 6YD UK; Anaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK; Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, University of Southampton, Tremona Road, Southampton, SO16 6YD UK.
Philip J HennisUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK.
Edward T Gilbert-KawaiUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK.
Bernadette O FernandezClinical & Experimental Sciences, Faculty of Medicine, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK; Warwick Medical School, Division of Metabolic and Vascular Health, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Matthieu PoudevigneClinical & Experimental Sciences, Faculty of Medicine, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK.
Alexandra CobbUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK.
Paula MealeUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK.
Kay MitchellCritical Care Research Area, Southampton NIHR Respiratory Biomedical Research Unit, Tremona Road, Southampton, SO16 6YD UK; Anaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK; Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, University of Southampton, Tremona Road, Southampton, SO16 6YD UK.
Helen MoysesClinical & Experimental Sciences, Faculty of Medicine, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK.
Helmut PöhnlAURAPA, Paul-Heidelbauer-Straße 26, 74321 Bietigheim-Bissingen, Germany.
Monty G MythenUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK.
Michael P W GrocottCritical Care Research Area, Southampton NIHR Respiratory Biomedical Research Unit, Tremona Road, Southampton, SO16 6YD UK; Anaesthesia and Critical Care Research Unit, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK; Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, University of Southampton, Tremona Road, Southampton, SO16 6YD UK.
Martin FeelischCritical Care Research Area, Southampton NIHR Respiratory Biomedical Research Unit, Tremona Road, Southampton, SO16 6YD UK; Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, University of Southampton, Tremona Road, Southampton, SO16 6YD UK; Clinical & Experimental Sciences, Faculty of Medicine, NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD UK; Warwick Medical School, Division of Metabolic and Vascular Health, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK. Electronic address: m.feelisch@soton.ac.uk.
Daniel S MartinUCL Centre for Altitude, Space and Extreme Environment (CASE) Medicine, UCLH NIHR Biomedical Research Centre, Institute of Sport Exercise & Health, 170 Tottenham Court Road, London, W1T 7HA, UK. Electronic address: daniel.martin@ucl.ac.uk.
Xtreme Alps research group
University College London · GBSouthampton General Hospital · GBUniversity Hospital Southampton NHS Foundation Trust · GBEnglish Institute of Sport · GB
Funding
Medical Research Council G0701115Medical Research Council MR/P008887/1
Abstract
Nitric oxide (NO) production plays a central role in conferring tolerance to hypoxia. Tibetan highlanders, successful high-altitude dwellers for millennia, have higher circulating nitrate and exhaled NO (E
Indexed as
Dietary SupplementsAdultAltitude SicknessBeta vulgarisFemaleFruit and Vegetable JuicesHumansLungMaleNitratesNitric OxideNitritesOxygenRespiratory RateSalivaNitratesNitric OxideNitritesOxygenAltitudeHypoxaemiaHypoxiaNitrateNitric oxideNitrite
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.