Evidence map›Paper›PMID 29042024›Full record

ReviewSeminars in immunology2017

The role of the LTB

Bhagawat C Subramanian, Ritankar Majumdar, Carole A Parent

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2021
    Trial
  3. KArchiv der Pharmazie · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lipoxin A4 AttenuatesJournal of inflammation research · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Neutrophil diversity and function in health and disease.Signal transduction and targeted therapy · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bhagawat C SubramanianLaboratory of Cellular and Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, United States. Electronic address: bhagawatchandrasekar.subramanian@nih.gov.
Ritankar MajumdarLaboratory of Cellular and Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, United States; Department of Pharmacology, University of Michigan School of Medicine, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, United States. Electronic address: ritankar@umich.edu.
Carole A ParentLaboratory of Cellular and Molecular Biology, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, United States; Department of Pharmacology, University of Michigan School of Medicine, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, United States. Electronic address: parentc@umich.edu.
Center for Cancer Research · US

Funding

CHEMOTACTIC SIGNALS REGULATING HUMAN NEUTROPHIL AND BREAST METASTATIC MIGRATIONZIABC011216 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PARENT, CAROLE · 2009 to 2017
$8.6M
Intramural NIH HHS ZIA BC011216
6 · The paper itself

Abstract

Directed leukocyte migration is a hallmark of inflammatory immune responses. Leukotrienes are derived from arachidonic acid and represent a class of potent lipid mediators of leukocyte migration. In this review, we summarize the essential steps leading to the production of LTB

Indexed as

AnimalsCell MovementChemotaxisHumansInflammationLeukocytesLeukotriene B4NeutrophilsReceptors, Leukotriene B4Signal TransductionLeukotriene B4LTB4R protein, humanReceptors, Leukotriene B4ChemotaxisInflammationLeukotriene B(4)MigrationNeutrophils

Identifiers

PMID29042024
PMCPMC8288505
OpenAlexW2766522579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.