ArticleJournal of physiological anthropology2017
Human pupillary light reflex during successive irradiation with 1-ms blue- and green-pulsed light.
Article in Journal of physiological anthropology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- "Blue Sky Effect": Contextual Influences on Pupil Size During Naturalistic Visual Search.Frontiers in psychology · 2021Article
- A review of the studies on nonvisual lighting effects in the field of physiological anthropology.Journal of physiological anthropology · 2019Review
- Suppression of salivary melatonin secretion under 100-Hz flickering and non-flickering blue light.Journal of physiological anthropology · 2018Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the human retina, the contribution of intrinsically photosensitive retinal ganglion cells (ipRGCs) to the regulation of the pupillary response remains poorly understood. The objective of the current study was to determine the response dynamics of the pupillary light reflex to short, successive pulses of light. In order to better assess the roles of ipRGCs and cones, we used pulses of blue and green light.
methodsEach participant was exposed to 1-ms blue (466 nm) and/or green (527 nm) light pulses simultaneously or separately, with inter-stimulus intervals (ISIs) of 0, 250, 500, 750, or 1000 ms. Pupil diameter was measured using an infrared camera system.
resultsWe found that human pupillary light responses during simultaneous irradiation or successive irradiation with ISIs ≤ 250 ms were equivalent, though successive irradiation of blue- and green-pulsed light with ISIs ≥ 500 ms induced markedly increased pupillary constriction.
conclusionsWe propose that this result may be related to cell hyperpolarization that occurs in the retina just after the first light stimulus is turned off, with the threshold for this effect being between 250 and 500 ms in the human retina.
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