Evidence map›Paper›PMID 29040924›Full record

ArticleResearch in developmental disabilities2017

Early social communication in infants with fragile X syndrome and infant siblings of children with autism spectrum disorder.

Laura J Hahn, Nancy C Brady, Lindsay McCary, Lisa Rague, Jane E Roberts

Open access · greenAbstract read
In one paragraph

Article in Research in developmental disabilities, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Prelinguistic Communication Complexity of Children With Neurogenetic Syndromes.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Motor Influences on Communication: Comparisons Between Down Syndrome and Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Initiating joint attention use in infants at high-risk for autism spectrum disorder.Journal of intellectual disability research : JIDR · 2018
    Article
  20. Early gesture use in fragile X syndrome.Journal of intellectual disability research : JIDR · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura J HahnLife Span Institute, University of Kansas, United States; Department of Psychology, University of South Carolina, United States; Department of Psychology, University of South Carolina, United States. Electronic address: ljhahn@illinois.edu.
Nancy C BradySpeech-Language-Hearing, Sciences & Disorders, University of Kansas, United States.
Lindsay McCaryDepartment of Psychology, University of South Carolina, United States.
Lisa RagueDepartment of Psychology, University of South Carolina, United States.
Jane E RobertsDepartment of Psychology, University of South Carolina, United States.
University of South Carolina · USUniversity of Kansas · US

Funding

UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7M
Research Design and Analysis Core (RDAC)P30HD002528 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI FOWLER, STEPHEN CLETIUS · 1985 to 2015
$22.1M
Supplement to The Emergence and Stability of Autism in Fragile X SyndromeR01MH090194 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI ROBERTS, JANE E · 2011 to 2020
$5.4M
The Effects of Parenting on the Development and Behavior of Adolescents with FXSR01HD084563 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI NANCY CAROLINE BRADY · 2016 to 2026
$4.7M
The CCS: A Treatment Outcome Measure for Individuals with Severe IDR01HD076903 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI BRADY, NANCY CAROLINE, FLEMING, KANDACE KAY · 2013 to 2017
$1.7M
Postdoctoral Training in Translational IDD ResearchT32HD057844 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI SAUNDERS, KATHRYN J · 2009 to 2013
$801k
NICHD NIH HHS P30 HD002528NICHD NIH HHS P30 HD003110NICHD NIH HHS R01 HD076903NICHD NIH HHS R01 HD084563NICHD NIH HHS T32 HD057844NIMH NIH HHS L40 MH108014NIMH NIH HHS R01 MH090194
6 · The paper itself

Abstract

backgroundLittle research in fragile X syndrome (FXS) has prospectively examined early social communication.

aimsTo compare early social communication in infants with FXS, infant siblings of children with autism spectrum disorder (ASIBs), and typically developing (TD) infants. METHODS AND PROCEDURES: Participants were 18 infants with FXS, 21 ASIBs, and 22 TD infants between 7.5-14.5 months. Social communication was coded using the Communication Complexity Scale during the administration of Autism Observation Scale for Infants. OUTCOMES AND

resultsDescriptively different patterns were seen across the three groups. Overall infants with FXS had lower social communication than ASIBs or TD infants when controlling for nonverbal cognitive abilities. However, infants with FXS had similar levels of social communication as ASIBs or TD infants during peek-a-boo. No differences were observed between ASIBs and TD infants. For all infants, higher social communication was related to lower ASD risk. CONCLUSIONS AND IMPLICATIONS: Findings provide insight into the developmental course of social communication in FXS. The dynamic nature of social games may help to stimulate communication in infants with FXS. Language interventions with a strong social component may be particularly effective for promoting language development in FXS.

Indexed as

CommunicationSocial BehaviorAutism Spectrum DisorderCase-Control StudiesFemaleFragile X SyndromeHumansInfantMaleSiblingsAutism spectrum disordersBehavioral phenotypeCommunication complexityFragile X syndromeSocial communication development

Identifiers

PMID29040924
PMCPMC5675817
OpenAlexW2763504159

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.