Evidence map›Paper›PMID 29040301›Full record

ArticlePloS one2017

Surveying predictors of late-life longitudinal change in daily activity energy expenditure.

Vincenzo Valiani, Sandrine Sourdet, Dale A Schoeller, Dawn C Mackey, Douglas C Bauer, Nancy W Glynn, Yosuke Yamada, Tamara B Harris, Todd M Manini, Health, Aging and Body Composition Study

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Vincenzo ValianiDepartment of Aging and Geriatric Research, University of Florida, Gainesville, Forida, United States of America.ORCID http://orcid.org/0000-0003-1841-3519
Sandrine SourdetGérontopôle, Hôpital La Grave-Casselardit, Toulouse, France.
Dale A SchoellerDepartment of Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
Dawn C MackeyDepartment of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, Canada.
Douglas C BauerDivision of General Internal Medicine, University of California, San Francisco, California, United States of America.
Nancy W GlynnDepartment of Epidemiology, Center for Aging and Population Health, Univeristy of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Yosuke YamadaDeparment of Nutritional Science, National Institute of Biomedical Innovation, Health and Nutrition, Tokyo, Japan.
Tamara B HarrisLaboratory of Epidemiology and Population Sciences, IRP, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.
Todd M ManiniDepartment of Aging and Geriatric Research, University of Florida, Gainesville, Forida, United States of America.
Health, Aging and Body Composition Study
University of Florida · USHôpital de La Grave · FRNational Institute of Biomedical Innovation, Health and Nutrition · JPNational Institutes of Health · USSimon Fraser University · CAUniversity of California, San Francisco · USUniversity of Pittsburgh · USUniversity of Wisconsin–Madison · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
Metabolic Costs of Daily Activities in Older AdultsR01AG042525 · NIA · UNIVERSITY OF FLORIDA · PI MANINI, TODD · 2013 to 2017
$1.6M
MtDNA variant modifiers of cardiopulmonary responsiveness to physical activityR01HL121023 · NHLBI · UNIVERSITY OF FLORIDA · PI FRAGOSO, CARLOS A. VAZ, MANINI, TODD · 2014 to 2017
$1.3M
NHLBI NIH HHS R01 HL121023NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG028050NIA NIH HHS R01 AG042525NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

backgroundTotal daily energy expenditure (TEE) is composed of resting metabolic rate (RMR), post-prandial thermogenesis and activity energy expenditure (AEE). Higher AEE is strongly associated with lower mortality and physical limitations among older adults, but factors that predict changes in AEE in septu and octogenarians are not clearly understood.

objectiveTo identify factors associated with late-life longitudinal change in AEE.

designEnergy expenditure was re-assessed in 83 participants (average age at baseline, 74.4±3.2 years)-an average of 7.5±0.54 years since the baseline measure. RMR was measured using indirect calorimetry and the thermic effect of meals was estimated at 10% of TEE. AEE was calculated as: TEE(0.9)-RMR. Participants were categorized into two groups according to the estimated day-to-day precision of the doubly-labeled water technique. Those who were within 10% or increased relative to their initial AEE measurement were categorized as having preserved AEE. Participants who declined greater than 10% of their initial measurement were categorized as having reduced AEE. A variety of socio-demographic, functional and mental factors, body composition, community and personal behaviors, blood measurements and health conditions were evaluated between groups at baseline and changes during follow-up.

resultsDaily AEE declined 106.61±293.25 kcal, which equated to a 14.63±40.57 kcal/d decrease per year. Fifty-nine percent (n = 49) preserved their AEE and 41% (n = 34) declined. Those who demonstrated a decline in AEE were older, had lower walking speed at baseline and showed a higher lean mass loss during follow up. Otherwise, groups were similar for socio-demographic characteristics, body composition, mental and physical function, health conditions and community and personal behaviors at baseline and change in these factors during follow-up.

conclusionsThis study demonstrates that AEE declines through the 8th decade of life and is associated with age, lower walking speed at baseline and lean mass loss. Additionally, there are a significant number of individuals who appear to be resilient to these declines despite having health events that are expected to have a negative impact on their physical activity.

Indexed as

AgedBasal MetabolismBody CompositionCalorimetry, IndirectEnergy MetabolismExerciseFemaleHumansMale

Identifiers

PMID29040301
PMCPMC5645098
OpenAlexW2765735003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.