Evidence map›Paper›PMID 29039984›Full record

ArticleAIDS patient care and STDs2017

Financial Barriers and Lapses in Treatment and Care of HIV-Infected Adults in a Southern State in the United States.

David A Wohl, Rita K Kuwahara, Kamran Javadi, Christine Kirby, David L Rosen, Sonia Napravnik, Claire Farel

Abstract read
In one paragraph

Article in AIDS patient care and STDs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Examining Depression as a Risk Factor for Cardiovascular Disease in People with HIV: A Systematic Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023
    Pooled it
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  13. Special Issue: Examining the Impacts of Social Determinants on HIV Health and Prevention.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David A Wohl1 University of North Carolina at Chapel Hill School of Medicine , Division of Infectious Diseases, Chapel Hill, North Carolina.
Rita K Kuwahara2 Emory School of Medicine , Atlanta, Georgia .
Kamran Javadi1 University of North Carolina at Chapel Hill School of Medicine , Division of Infectious Diseases, Chapel Hill, North Carolina.
Christine Kirby3 Duke University School of Medicine , Durham, North Carolina.
David L Rosen1 University of North Carolina at Chapel Hill School of Medicine , Division of Infectious Diseases, Chapel Hill, North Carolina.
Sonia Napravnik1 University of North Carolina at Chapel Hill School of Medicine , Division of Infectious Diseases, Chapel Hill, North Carolina.
Claire Farel1 University of North Carolina at Chapel Hill School of Medicine , Division of Infectious Diseases, Chapel Hill, North Carolina.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

Antiretroviral (ARV) adherence has largely been considered from the perspective of an individual's behavior with less attention given to potential structural causes for lapses in treatment, such as the cost of medications and care. HIV medication expense is typically covered by third party payers. However, private insurance premiums and deductibles may rise, or policies terminated such as with a change in employment. Likewise, a patient's eligibility for publicly funded coverage like state AIDS Drug Assistance Programs (ADAP) or Medicaid can also be lost. We conducted a one-time survey of a sample of 300 patients receiving HIV care at a single large academic center in the south of United States to examine lapses in HIV therapy due to financial reasons. We found that during the prior year, financial issues including medication cost or coverage led to a lapse in ARVs in 10% (n = 31) of participants. However, of the 42% (n = 125) participants who had been enrolled in ADAP at any time during the prior year, 21% (n = 26) reported an ARV lapse due to problems with ADAP or medication cost. Respondents cited ADAP's required semi-annual renewal process and other administrative issues as the cause of ARV lapses. The median duration of missed ARVs was 2 weeks (range of <1-23 weeks). Non-HIV medication and transportation to and from clinic costs were also identified as financial burdens to care by respondents. In conclusion, although conducted at a single medical center and one state, this study suggests that a significant minority of HIV-infected patients encounter financial barriers to ARV access, and this is paradoxically more common among those enrolled in the state ADAP. Streamlining, supporting, and simplifying ADAP renewal procedures will likely reduce lapses in ARV adherence and persistence.

Indexed as

Government ProgramsAdultAmbulatory Care FacilitiesAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveFemaleHealth Services AccessibilityHIV InfectionsHumansMaleMedicaidMedication AdherenceUnited StatesAnti-HIV Agentsaccess to careantiretroviraldrug costpatient care

Identifiers

PMID29039984
PMCPMC5665096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.