ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Effects of Copaiba oil in the healing process of urinary bladder in rats.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Skin Tear Treatment withPharmaceuticals (Basel, Switzerland) · 2024Article
- Toxicological Effects of Copaiba Oil (Plants (Basel, Switzerland) · 2023Review
- Fast-Acting and Receptor-Mediated Regulation of Neuronal Signaling Pathways by Copaiba Essential Oil.International journal of molecular sciences · 2020Article
- Effect of a high-fat diet on the rat bladder wall and bioactive action of Brazil nut oil.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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6 authors.
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Abstract
introductionThe appropriate closure of the urinary bladder is important to many urologic procedures to avoid the formation of fistulas and strictures by excessive fibrosis. This paper presents the alterations in the bladder healing process of rats after the topical use of Copaiba oil (Copaifera reticulata). MATERIAL AND
methodsTen male Wistar rats were used and randomly divided into two groups: Control group (CG): injected 1ml/kg of saline solution on the suture line; and Copaiba group (CpG): 0.63ml/kg of copaiba oil applied to the suture line. Euthanasia was performed on the seventh day after surgery. The criteria observed were adherences formation, histopathological modifications and stereology for collagen.
resultsBoth groups showed adhesions to the bladder, with no statistically significant difference (p=0.1481). The microscopic evaluation revealed a trend to more severe acute inflammation process on the CpG, but there was statistical difference only in the giant cells reaction (p=0.0472) and vascular proliferation (p=0.0472). The stereology showed no difference.
conclusionThe copaiba oil modified the healing process, improving the quantity of giant cells and vascular proliferation, but not interfered in the collagen physiology.
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