ArticleOrganic letters2017
Rapid Access to a Broad Range of 6'-Substituted Firefly Luciferin Analogues Reveals Surprising Emitters and Inhibitors.
Article in Organic letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Antitubercular activity of 2-mercaptobenzothiazole derivatives targetingRSC medicinal chemistry · 2024Article
- One-pot Synthesis and Photophysical Studies of Α-cycloamino-substituted 5-aryl-2,2'-bipyridines.Journal of fluorescence · 2024Article
- Firefly luciferin methyl ester illuminates the activity of multiple serine hydrolases.Chemical communications (Cambridge, England) · 2023Article
- Bioluminogenic Probe for Rapid, Ultrasensitive Detection of β-Lactam-Resistant Bacteria.Analytical chemistry · 2023Article
- Computational Investigation of Substituent Effects on the Fluorescence Wavelengths of Oxyluciferin Analogs.Journal of photochemistry and photobiology. A, Chemistry · 2022Article
- Silicon functionalization expands the repertoire of Si-rhodamine fluorescent probes.Chemical science · 2022Article
- Environment-Sensitive Fluorescent Labelling of Peptides by Luciferin Analogues.International journal of molecular sciences · 2021Article
- Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II-Design, Synthesis, and Evaluation.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Molecular Design of d-Luciferin-Based Bioluminescence and 1,2-Dioxetane-Based Chemiluminescence Substrates for Altered Output Wavelength and Detecting Various Molecules.Molecules (Basel, Switzerland) · 2021Review
- Seeing (and Using) the Light: Recent Developments in Bioluminescence Technology.Cell chemical biology · 2020Review
- Bioluminescence imaging in mice with synthetic luciferin analogues.Methods in enzymology · 2020Article
- Building Biological Flashlights: Orthogonal Luciferases and Luciferins forAccounts of chemical research · 2019Review
- Sulfonamides Are an Overlooked Class of Electron Donors in Luminogenic Luciferins and Fluorescent Dyes.Organic letters · 2019Article
- Computational investigation into the fluorescence of luciferin analogues.Journal of computational chemistry · 2019Article
- Silicon Substitution in Oxazine Dyes Yields Near-Infrared Azasiline Fluorophores That Absorb and Emit beyond 700 nm.Organic letters · 2018Article
- Advances in bioluminescence imaging: new probes from old recipes.Current opinion in chemical biology · 2018Review
- Lessons Learned from Luminous Luciferins and Latent Luciferases.ACS chemical biology · 2018Review
- Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine-Lysine Relay.The Journal of organic chemistry · 2018Article
- Novel caged luciferin derivatives can prolong bioluminescence imagingRSC advances · 2018Article
- Luciferase Activity of Insect Fatty Acyl-CoA Synthetases with Synthetic Luciferins.ACS chemical biology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Light-emitting firefly luciferin analogues contain electron-donating groups in the 6'-position, but the scope of known 6'-substitution remains narrow. A two-step route to a broad range of 6'-substituted luciferin analogues was developed to fill this void and enable more extensive study of the 6'-functionality. This chemistry allowed direct access to "caged" amide and bright azetidine analogues, but also revealed thioether inhibitors and unexpectedly luminogenic aryl amine derivatives.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.