ArticleJournal of the International Neuropsychological Society : JINS2018
Visuospatial Functioning in the Primary Progressive Aphasias.
Article in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.Annals of neurology · 2018Pooled it
- Atypical Alzheimer disease: a multi-axis framework toward defining heterogeneity.Nature reviews. Neurology · 2026Review
- Beyond language: A structured profile of number processing impairment in logopenic primary progressive aphasia.Journal of Alzheimer's disease : JAD · 2026Article
- Multidimensional cognitive deficits in the typical and atypical variants of Alzheimer's disease.Alzheimer's research & therapy · 2025Article
- The curious case of the Cat Rescue: can picture narrative description inform visuospatial processing in aphasia?Frontiers in human neuroscience · 2025Article
- Assessing processing speed and its neural correlates in the three variants of primary progressive aphasia with a non-verbal tablet-based task.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- The neural substrates of transdiagnostic cognitive-linguistic heterogeneity in primary progressive aphasia.Alzheimer's research & therapy · 2023Article
- Distinct neurophysiology during nonword repetition in logopenic and non-fluent variants of primary progressive aphasia.Human brain mapping · 2023Article
- APOE ε4 influences within and between network functional connectivity in posterior cortical atrophy and logopenic progressive aphasia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Network anatomy in logopenic variant of primary progressive aphasia.Human brain mapping · 2023Article
- Altered within- and between-network functional connectivity in atypical Alzheimer's disease.Brain communications · 2023Article
- Diffusivity Changes in Posterior Cortical Atrophy and Logopenic Progressive Aphasia: A Longitudinal Diffusion Tensor Imaging Study.Journal of Alzheimer's disease : JAD · 2023Article
- Understanding the multidimensional cognitive deficits of logopenic variant primary progressive aphasia.Brain : a journal of neurology · 2022Review
- Article
- Neuropsychological Profiles of Patients with Progressive Apraxia of Speech and Aphasia.Journal of the International Neuropsychological Society : JINS · 2022Article
- The natural history of primary progressive aphasia: beyond aphasia.Journal of neurology · 2022Article
- Clinical and neuroimaging characteristics of primary progressive aphasia.Handbook of clinical neurology · 2022Review
- Neuroanatomical correlations of visuospatial processing in primary progressive aphasia.Brain communications · 2022Article
- Utility of the Addenbrooke's Cognitive Examination III online calculator to differentiate the primary progressive aphasia variants.Brain communications · 2022Article
- Frontotemporal dementia: A unique window on the functional role of the temporal lobes.Handbook of clinical neurology · 2022Review
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14 authors.
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Abstract
objectivesThe aim of this study was to identify whether the three main primary progressive aphasia (PPA) variants would show differential profiles on measures of visuospatial cognition. We hypothesized that the logopenic variant would have the most difficulty across tasks requiring visuospatial and visual memory abilities.
methodsPPA patients (n=156), diagnosed using current criteria, and controls were tested on a battery of tests tapping different aspects of visuospatial cognition. We compared the groups on an overall visuospatial factor; construction, immediate recall, delayed recall, and executive functioning composites; and on individual tests. Cross-sectional and longitudinal comparisons were made, adjusted for disease severity, age, and education.
resultsThe logopenic variant had significantly lower scores on the visuospatial factor and the most impaired scores on all composites. The nonfluent variant had significant difficulty on all visuospatial composites except the delayed recall, which differentiated them from the logopenic variant. In contrast, the semantic variants performed poorly only on delayed recall of visual information. The logopenic and nonfluent variants showed decline in figure copying performance over time, whereas in the semantic variant, this skill was remarkably preserved.
conclusionsThis extensive examination of performance on visuospatial tasks in the PPA variants solidifies some previous findings, for example, delayed recall of visual stimuli adds value in differential diagnosis between logopenic variant PPA and nonfluent variant PPA variants, and illuminates the possibility of common mechanisms that underlie both linguistic and non-linguistic deficits in the variants. Furthermore, this is the first study that has investigated visuospatial functioning over time in the PPA variants. (JINS, 2018, 24, 259-268).
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