Evidence map›Paper›PMID 29039256›Full record

ArticleThe New bioethics : a multidisciplinary journal of biotechnology and the body2017

Ethical Considerations in Microbial Therapeutic Clinical Trials.

Michael H Woodworth, Kaitlin L Sitchenko, Cynthia Carpentieri, Rachel J Friedman-Moraco, Tiffany Wang, Colleen S Kraft

Abstract read
In one paragraph

Article in The New bioethics : a multidisciplinary journal of biotechnology and the body, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael H Woodwortha Department of Medicine, Division of Infectious Diseases , Emory University School of Medicine , Atlanta , GA , USA.ORCID http://orcid.org/0000-0002-6181-4599
Kaitlin L Sitchenkoa Department of Medicine, Division of Infectious Diseases , Emory University School of Medicine , Atlanta , GA , USA.
Cynthia Carpentieria Department of Medicine, Division of Infectious Diseases , Emory University School of Medicine , Atlanta , GA , USA.
Rachel J Friedman-Moracoa Department of Medicine, Division of Infectious Diseases , Emory University School of Medicine , Atlanta , GA , USA.
Tiffany Wangb Emory University School of Medicine , Atlanta , GA , USA.
Colleen S Krafta Department of Medicine, Division of Infectious Diseases , Emory University School of Medicine , Atlanta , GA , USA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378
6 · The paper itself

Abstract

As understanding of the human microbiome improves, novel therapeutic targets to improve human health with microbial therapeutics will continue to expand. We outline key considerations of balancing risks and benefits, optimising access, returning key results to research participants, and potential conflicts of interest.

Indexed as

Clinical Trials as TopicClostridioides difficileClostridium InfectionsFecal Microbiota TransplantationGastrointestinal MicrobiomeHumansClostridium difficileethicsfecal microbiota transplantFMTmicrobiomerecurrent Clostridium difficile

Identifiers

PMID29039256
PMCPMC5996990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.