Evidence map›Paper›PMID 29039225›Full record

ReviewInhalation toxicology2017

Toxicological impact of waterpipe smoking and flavorings in the oral cavity and respiratory system.

Fawad Javed, Shatha Subhi ALHarthi, Munerah Saleh BinShabaib, Sangeeta Gajendra, Georgios E Romanos, Irfan Rahman

Open access · greenAbstract readReview
In one paragraph

Review in Inhalation toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Toxicity of waterpipe tobacco smoking: the role of flavors, sweeteners, humectants, and charcoal.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Fawad Javeda Department of General Dentistry , Eastman Institute for Oral Health, University of Rochester , Rochester , NY , USA.
Shatha Subhi ALHarthib Department of Periodontology, College of Dentistry , Princess Nourah Bint Abdulrahman University , Riyadh , Kingdom of Saudi Arabia.
Munerah Saleh BinShabaibb Department of Periodontology, College of Dentistry , Princess Nourah Bint Abdulrahman University , Riyadh , Kingdom of Saudi Arabia.
Sangeeta Gajendrac Department of Community Dentistry , Eastman Institute for Oral Health, University of Rochester , Rochester , NY , USA.
Georgios E Romanosd Department of Periodontology, School of Dental Medicine , Stony Brook University , Stony Brook , NY , USA.
Irfan Rahmane Department of Environmental Medicine, School of Medicine and Dentistry , University of Rochester , Rochester , NY , USA.
University of Rochester · USPrincess Nourah bint Abdulrahman University · SAStony Brook School · US

Funding

MECHANISMS OF CIGARETTE SMOKE-INDUCED LUNG CELLULAR SENESCENCER01HL085613 · NHLBI · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN · 2007 to 2017
$4.0M
Inflammatory and Dysregulated Repair Responses to Inhaled NicotineR01HL135613 · NHLBI · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN · 2017 to 2021
$2.7M
TOPOGRAPHY, CONSTITUENTS, AND TOXICITY OF WATERPIPE TOBACCO SMOKE UNDER REALISTIC CONDITIONSR01DA042470 · NIDA · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN, ROBINSON, RISA JEAN · 2016 to 2018
$1.1M
NHLBI NIH HHS R01 HL085613NHLBI NIH HHS R01 HL135613NIDA NIH HHS R01 DA042470
6 · The paper itself

Abstract

Waterpipe smoking (WS), an emerging trend has major health concerns. It is prevalent worldwide as a recreational activity both indoors and outdoors. The aim of this review was to assess the impact of waterpipe smoke on the oral and respiratory system (oral cavity and pulmonary tissues). A number of studies have shown that periodontal health status is compromised in waterpipe smokers when compared with nonsmokers. Some studies have associated WS with oral premalignant and malignant lesions; however, due to the poor quality of these studies, the presented outcomes should be interpreted with caution. Although cigarette smoking has been considered as a potential risk factor for dental caries; there are no studies in indexed literature that have shown an association to exist between dental caries and WS. Inhaled waterpipe smoke imposes oxidative stress and inflammatory responses and compromises the ventilatory capacity of the lungs and may lead to an increased risk of decline in lung function. WS may cause oral and pulmonary diseases, such as periodontal disease and chronic obstructive airway disease, respectively. The association between WS and development of dental caries and oral pre-cancer and their relationships with chronic airways disease requires investigations. This review discusses the current evidence of waterpipe smoke effects on the oral health and respiratory system based on basic and clinical science and provides future directions for research and regulatory science on how WS can affect the oral cavity and the respiratory/pulmonary system.

Indexed as

AnimalsFlavoring AgentsHumansMouthNicotianaRespiratory SystemWater Pipe SmokingFlavoring AgentscancerCOPDDentalhookahnarghileoralperiodontalpulmonarysmoking waterpipe

Identifiers

PMID29039225
PMCPMC5927775
OpenAlexW2766324715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.