Evidence map›Paper›PMID 29038964›Full record

ArticleInternational journal of colorectal disease2018

Surgical and oncological outcomes after complete mesocolic excision in right-sided colon cancer compared with conventional surgery: a retrospective, single-institution study.

Tommaso Zurleni, Alberto Cassiano, Elson Gjoni, Andrea Ballabio, Giovanni Serio, Luca Marzoli, Francesco Zurleni

Erratum issuedAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 7 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 7 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  8. Prognostic factors of non-metastatic right colon adenocarcinoma: A multicentre retrospective analysis from the ATCCR database.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tommaso ZurleniDepartment of General Surgery, Hospital of Busto Arsizio (Va), Piazzale Solaro 3, 21052, Busto Arsizio, Italy. tzurleni@yahoo.it.ORCID http://orcid.org/0000-0002-3971-2297
Alberto CassianoDepartment of General Surgery, Hospital of Busto Arsizio (Va), Piazzale Solaro 3, 21052, Busto Arsizio, Italy.
Elson GjoniDepartment of General Surgery, Hospital of Busto Arsizio (Va), Piazzale Solaro 3, 21052, Busto Arsizio, Italy.
Andrea BallabioDepartment of General Surgery, Hospital of Busto Arsizio (Va), Piazzale Solaro 3, 21052, Busto Arsizio, Italy.
Giovanni SerioDepartment of Anatomical Pathology, Hospital of Busto Arsizio, Busto Arsizio, Italy.
Luca MarzoliDepartment of Medical Physics, Hospital of Busto Arsizio, Busto Arsizio, Italy.
Francesco ZurleniDepartment of General Surgery, Hospital of Busto Arsizio (Va), Piazzale Solaro 3, 21052, Busto Arsizio, Italy.
Ospedale di Circolo di Busto Arsizio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the study was whether complete mesocolic excision (CME) with central vascular ligation (CVL) is associated with a survival benefit compared with traditional procedure in right-sided colon cancer.

methodsOverall, 251 consecutive patients underwent surgery for right colon cancer between 2007 and 2012. After exclusion, 95 subjects received non-CME surgery before 2010, and 97 subjects received CME surgery after January 2010, when we started to perform CME systematically. The number of lymph nodes, morbidity, and mortality was analyzed. Overall survival (OS) and disease-specific survival (DSS) were investigated.

resultsThe median number of examined lymph nodes was 33.28 in the CME group and 26.92 in the non-CME group, p < 0.001. Postoperative complications were 21.6% in the CME group and 17.8% in the non-CME group, without significant difference. One out of 192 patients died. Three-year OS was 88% in the CME group and 71% in the non-CME group (p = 0.003). In stage II, 3-year DSS was 97% in the CME group and 86% in the non-CME group. In stage III, the 3-year DSSs in the CME and in the non-CME groups were 86 and 67%, respectively (p < 0.001). Cox's regression showed that CME (p = 0.0012), the number of lymph nodes (p = 0.029), and TNM stage (p < 0.001) were significant independent predictors of DSS at 3 years.

conclusionSurgical standardization of CME with CVL for right-sided colon cancer is associated with better staging and prognosis, particularly in UICC stage II and III. This study shows that CME is safe and reproducible with acceptable morbidity.

Indexed as

AgedColonic NeoplasmsDisease-Free SurvivalDissectionEndpoint DeterminationFemaleHumansLymph Node ExcisionMaleMesocolonPostoperative ComplicationsRetrospective StudiesTreatment OutcomeCentral vascular ligationComplete mesocolic excisionLymph node dissectionRight-sided colon cancerStandardized surgery

Identifiers

PMID29038964
OpenAlexW2766846761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.