Evidence map›Paper›PMID 29038793›Full record

ArticleCurrent opinion in systems biology2017

Mechanisms of Cell Polarization.

Wouter-Jan Rappel, Leah Edelstein-Keshet

Abstract read
In one paragraph

Article in Current opinion in systems biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
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  5. Emergent eukaryotic directional sensing via receptor degradation and diffusion.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. pH-regulated single cell migration.Pflugers Archiv : European journal of physiology · 2024
    Review
  13. Mesenchymal cell migration on one-dimensional micropatterns.Frontiers in cell and developmental biology · 2024
    Review
  14. Migration and division in cell monolayers on substrates with topological defects.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wouter-Jan RappelDepartment of Physics, University of California, San Diego, La Jolla, USA.
Leah Edelstein-KeshetDepartment of Mathematics, University of British Columbia, Vancouver BC, V6T 1Z2.

Funding

Project 5P01GM078586 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAPPEL, WOUTER-JAN · 2007 to 2016
$11.2M
NIGMS NIH HHS P01 GM078586
6 · The paper itself

Abstract

Cell polarization is a key step in the migration, development, and organization of eukaryotic cells, both at the single cell and multicellular level. Research on the mechanisms that give rise to polarization of a given cell, and organization of polarity within a tissue has led to new understanding across cellular and developmental biology. In this review, we describe some of the history of theoretical and experimental aspects of the field, as well as some interesting questions and challenges for the future.

Identifiers

PMID29038793
PMCPMC5640326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.