Evidence map›Paper›PMID 29038659›Full record

ArticleFrontiers in immunology2017

Rune A Høglund, Andreas Lossius, Jorunn N Johansen, Jane Homan, Jūratė Šaltytė Benth, Harlan Robins, Bjarne Bogen, Robert D Bremel, Trygve Holmøy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. CD4Frontiers in immunology · 2020
    Article
  6. B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Rune A HøglundDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Andreas LossiusDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Jorunn N JohansenFaculty of Medicine, Department of Immunology and Transfusion Medicine, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway.
Jane HomanEigenBio LLC, Madison, WI, United States.
Jūratė Šaltytė BenthInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Harlan RobinsAdaptive Biotechnologies, Seattle, WA, United States.
Bjarne BogenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.
Robert D BremelEigenBio LLC, Madison, WI, United States.
Trygve HolmøyDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Akershus University Hospital · NOOslo University Hospital · NOUniversity of Oslo · NOAdaptive Biotechnologies (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory B cells acting as antigen-presenting cells are believed to be important in multiple sclerosis (MS), but the antigen they present remains unknown. We hypothesized that B cells may activate CD4

Indexed as

B cellbioinformaticsidiotopeimmunoglobulinimmunoglobulin heavy variableimmunosequencingmultiple sclerosisT cell

Identifiers

PMID29038659
PMCPMC5630699
OpenAlexW2764277357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.