Evidence map›Paper›PMID 29038590›Full record

ArticleScientific reports2017

Chronic hepatitis C liver microenvironment: role of the Th17/Treg interplay related to fibrogenesis.

Daniela Alejandra Rios, Pamela Valva, Paola Cecilia Casciato, Silvia Frias, María Soledad Caldirola, María Isabel Gaillard, Liliana Bezrodnik, Juan Bandi, Omar Galdame, Beatriz Ameigeiras and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. A TNature aging · 2023
    Article
  2. Article
  3. Article
  4. Viral hepatitis update: Progress and perspectives.World journal of gastroenterology · 2021
    Review
  5. Modulating effects of the probioticExperimental and therapeutic medicine · 2021
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Lymphocyte Landscape after ChronicInternational journal of molecular sciences · 2020
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Daniela Alejandra RiosInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA) Laboratorio de Biología Molecular, División Patología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD, Buenos Aires, Argentina. rios.daniela.89@gmail.com.ORCID 0000-0002-7384-2925
Pamela ValvaInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA) Laboratorio de Biología Molecular, División Patología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD, Buenos Aires, Argentina.
Paola Cecilia CasciatoUnidad de Hepatología, Hospital Italiano de Buenos Aires; Juan D Perón 4190, C1181ACH, Buenos Aires, Argentina.
Silvia FriasUnidad de Hepatología, Hospital Ramos Mejía; Urquiza 609, CP1221, Buenos Aires, Argentina.
María Soledad CaldirolaInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA), Departamento de Inmunología, Hospital de Niños Ricardo Gutiérrez; Gallo, 1330 C1425EFD, Buenos Aires, Argentina.
María Isabel GaillardInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA), Departamento de Inmunología, Hospital de Niños Ricardo Gutiérrez; Gallo, 1330 C1425EFD, Buenos Aires, Argentina.
Liliana BezrodnikInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA), Departamento de Inmunología, Hospital de Niños Ricardo Gutiérrez; Gallo, 1330 C1425EFD, Buenos Aires, Argentina.
Juan BandiUnidad de Hepatología, Hospital Italiano de Buenos Aires; Juan D Perón 4190, C1181ACH, Buenos Aires, Argentina.
Omar GaldameUnidad de Hepatología, Hospital Italiano de Buenos Aires; Juan D Perón 4190, C1181ACH, Buenos Aires, Argentina.
Beatriz AmeigeirasUnidad de Hepatología, Hospital Ramos Mejía; Urquiza 609, CP1221, Buenos Aires, Argentina.
Diana KrasnianskyUnidad de Hepatología, Hospital General de Agudos "Carlos G. Durand"; Av Díaz Vélez 5044, C1405DCS, Buenos Aires, Argentina.
Carlos BrodersenUnidad de Hepatología, Hospital General de Agudos "Carlos G. Durand"; Av Díaz Vélez 5044, C1405DCS, Buenos Aires, Argentina.
Eduardo MullenDivisión Patología, Hospital Italiano de Buenos Aires; Juan D Perón 4190, C1181ACH, Buenos Aires, Argentina.
Elena Noemí De MatteoInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA) Laboratorio de Biología Molecular, División Patología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD, Buenos Aires, Argentina.
María Victoria PreciadoInstituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP- CONICET-GCBA) Laboratorio de Biología Molecular, División Patología, Hospital de Niños Ricardo Gutiérrez, Gallo 1330, C1425EFD, Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARHospital Italiano de Buenos Aires · AREl Hospital General de Agudos Carlos G. Durand · ARHospital Ramos Mejía · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the different lymphocyte populations in liver microenvironment of chronic hepatitis C (CHC) patients is still matter of debate. Since Th17 and Treg have opposite functions, their balance could affect disease progression. The aim was to explore liver microenvironment and its peripheral blood counterpart in adult CHC patients. CD4

Indexed as

Cellular MicroenvironmentAdultAgedBiomarkersBiopsyCell CommunicationFemaleFluorescent Antibody TechniqueHepatitis C, ChronicHumansImmunohistochemistryImmunophenotypingLiver CirrhosisLiver Function TestsMaleMiddle AgedBiomarkers

Identifiers

PMID29038590
PMCPMC5643436
OpenAlexW2762294594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.