ArticleScientific reports2017
Use of pulmonary CT angiography with low tube voltage and low-iodine-concentration contrast agent to diagnose pulmonary embolism.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 22 citations in OpenAlex.
- Improving Diagnostic Accuracy in Acute Pulmonary Embolism: Insights from Spectral Dual-energy CT.Current medical imaging · 2025Article
- When can coronary computed tomography angiography in patients with calcified plaque be accurate?Frontiers in cardiovascular medicine · 2025Article
- Diagnostic Performance of Quantitative Computed Tomography Pulmonary Angiography Parameters in Patients With Pulmonary Embolism.Pulmonary medicine · 2025Article
- Artificial intelligence-based pulmonary embolism classification: Development and validation using real-world data.PloS one · 2024Article
- Automated detection, segmentation and measurement of major vessels and the trachea in CT pulmonary angiography.Scientific reports · 2023Article
- Identification of pulmonary embolism: diagnostic accuracy of venous-phase dual-energy CT in comparison to pulmonary arteries CT angiography.European radiology · 2021Article
- Optimization of computed tomography pulmonary angiography protocols using 3D printed model with simulation of pulmonary embolism.Quantitative imaging in medicine and surgery · 2019Article
- State-of-the-Art Imaging for the Evaluation of Pulmonary Embolism.Current treatment options in cardiovascular medicine · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary CT angiography (CTPA) is regarded as the preferred imaging method in diagnosing pulmonary embolism (PE). Considering the harm of radiation exposure and the side effect of iodinated contrast agent, CTPA protocol with low tube voltage and low dose of contrast agent became research hotspot in last decade. The present study evaluates the image quality, radiation dose, positive rate of PE and the location of PE with a CTPA protocol using low tube voltage (80 kVp) and low-iodine-concentration contrast agent (270 mg I/ml) in patients suspected of PE compared to a conventional CTPA protocol (120 kVp, 350 mg I/ml). The results showed that 80 kVp CTPA protocol with 40 ml 270 mg I/ml achieved equally subjective image quality and a positive rate for diagnosing PE, though the quantitative image quality was reduced compared to the 120 kVp CTPA protocol with 40 ml 350 mg I/ml administered, with a 63.6% decrease in radiation dose and a 22.9% reduction in iodine content of contrast agent. Our results document that CTPA protocol with low tube voltage and low iodine concentration of contrast agent is satisfied to the clinical application.
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