Evidence map›Paper›PMID 29038560›Full record

ArticleScientific reports2017

Safety assessment of antibiotic and probiotic feed additives for Gallus gallus domesticus.

D P Neveling, L van Emmenes, J J Ahire, E Pieterse, C Smith, L M T Dicks

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  7. Screening and Characterization ofAntioxidants (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D P NevelingDepartment of Microbiology, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa.ORCID 0000-0003-4090-9684
L van EmmenesDepartment of Animal Science, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa.
J J AhireDepartment of Microbiology, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa.ORCID 0000-0002-1142-8630
E PieterseDepartment of Animal Science, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa.
C SmithDepartment of Physiological Sciences, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa.ORCID 0000-0001-5924-9204
L M T DicksDepartment of Microbiology, University of Stellenbosch, Private BagX1, Matieland, 7602, Stellenbosch, South Africa. LMTD@sun.ac.za.
Stellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics in feed select for resistant strains and is thus a threat to human health. In this study, the effect of a multi-strain probiotic and antibiotics on the growth and health of broilers was studied. Equal numbers of broilers received on a daily basis either a multi-strain probiotic or a combination of sulphadiazine, colistin and trimethoprim, whereas the control group received standard feed. The villi of immature broilers (19 days old) administered antibiotics had a larger surface area and their lymphocyte and basophil counts were higher compared to broilers from the probiotic and control groups. The cecal microbiomes of mature broilers (29 days old) that received probiotics had higher levels of Enterobacteriaceae, but lower numbers of Clostridiales, Brucellaceae, Synergistaceae, Erysipelotrichaceae and Coriobacteriaceae compared to the antibiotic-treated group. A decline in the bioluminescence of Listeria monocytogenes observed for broilers on probiotics suggested that the probiotic may be used to control bacterial infections. No significant differences in total red blood cell, haemoglobin and haematocrit content, and mean values for corpuscular volume, corpuscular haemoglobin and corpuscular haemoglobin numbers were recorded amongst broilers from the different treatment groups. This study provides valuable information on the health and performance of broilers when administered probiotics and antibiotics as additives.

Indexed as

Animal FeedAnimalsAnti-Bacterial AgentsBacteriaBiodiversityCalcification, PhysiologicChickensGastrointestinal TractListeria monocytogenesMicrovilliOrgan SizePhylogenyProbioticsTibiaAnti-Bacterial Agents

Identifiers

PMID29038560
PMCPMC5643334
OpenAlexW2763496224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.