Evidence map›Paper›PMID 29038532›Full record

ArticleScientific reports2017

The major outer sheath protein forms distinct conformers and multimeric complexes in the outer membrane and periplasm of Treponema denticola.

Robbins Puthenveetil, Sanjiv Kumar, Melissa J Caimano, Abhishek Dey, Arvind Anand, Olga Vinogradova, Justin D Radolf

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Emerging oralFrontiers in oral health · 2025
    Article
  7. Article
  8. Article
  9. Oral and intestinal bacterial exotoxins: Potential linked to carcinogenesis.Progress in molecular biology and translational science · 2020
    Review
  10. Article
  11. Review
  12. Immunotopological Analysis of theJournal of bacteriology · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Robbins PuthenveetilDepartment of Molecular and Cell Biology, University of Connecticut, 91 North Eagleville Road, Storrs, CT, USA.
Sanjiv KumarDepartment of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT, USA.ORCID 0000-0003-3514-8999
Melissa J CaimanoDepartment of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT, USA.
Abhishek DeyDepartment of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT, USA.
Arvind AnandDepartment of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT, USA.
Olga VinogradovaDepartment of Pharmaceutical Sciences, University of Connecticut, 69 North Eagleville Road, Storrs, CT, USA.
Justin D RadolfDepartment of Medicine, UConn Health, 263 Farmington Avenue, Farmington, CT, USA. JRadolf@uchc.edu.
UConn Health · USUniversity of Connecticut · US

Funding

RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
Treponema pallidum Outer Membrane Proteins and Transition Metal AcquisitionR01AI026756 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI RADOLF, JUSTIN D · 1992 to 2017
$5.1M
T.pallidum Membrane Immunogens and Anti-Oxidant DefenseR37AI026756 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2002 to 2006
$1.8M
RpoS Regulation of Borrelia burgdorferi Genes in vivoR56AI029735 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2012 to 2012
$536k
NIAID NIH HHS R01 AI026756NIAID NIH HHS R01 AI029735NIAID NIH HHS R37 AI026756NIAID NIH HHS R56 AI029735
6 · The paper itself

Abstract

The major outer sheath protein (MOSP) is a prominent constituent of the cell envelope of Treponema denticola (TDE) and one of its principal virulence determinants. Bioinformatics predicts that MOSP consists of N- and C-terminal domains, MOSP

Indexed as

Bacterial Outer Membrane ProteinsBacterial ProteinsEscherichia coliEscherichia coli ProteinsMass SpectrometryPeriplasmTreponema denticolaBacterial Outer Membrane ProteinsBacterial ProteinsEscherichia coli Proteins

Identifiers

PMID29038532
PMCPMC5643300
OpenAlexW2762039002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.