ArticleScientific reports2017
A Study of the Brain Abnormalities of Post-Stroke Depression in Frontal Lobe Lesion.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis.Journal of the American Heart Association · 2022Pooled it
- Mechanisms of Repetitive Transcranial Magnetic Stimulation on Post-stroke Depression: A Resting-State Functional Magnetic Resonance Imaging Study.Brain topography · 2022Trial
- Exploring Gray Matter Alterations in Post-Stroke Patients: A Structural Covariance Analysis.Brain and behavior · 2026Article
- Basic and clinical research on acupuncture for post-stroke depression: A narrative review.World journal of methodology · 2026Review
- Bibliometric Analysis of the Post-Stroke Depression (1985-2024).Brain and behavior · 2026Review
- Lower reward sensitivity in frontostriatal stroke: Influence of depression and resting-state functional connectivity.Cognitive, affective & behavioral neuroscience · 2025Article
- Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis.Frontiers in pharmacology · 2025Review
- Post stroke depression: pathogenesis and molecular mechanisms of natural product-based interventions.Frontiers in pharmacology · 2025Review
- Alterations of contralesional hippocampal subfield volumes and relations to cognitive functions in patients with unilateral stroke.Brain and behavior · 2024Article
- Abnormal intrinsic functional hubs and connectivity in patients with post-stroke depression.Annals of clinical and translational neurology · 2024Article
- Post-stroke arrhythmia could be a potential predictor for post-stroke depression.Scientific reports · 2024Article
- Irritability in stroke: a protocol for a prospective study.Frontiers in neurology · 2024Article
- Neuroanatomy of post-stroke depression: the association between symptom clusters and lesion location.Brain communications · 2023Article
- The characteristics of brain network in patient with post-stroke depression under cognitive task condition.Frontiers in neuroscience · 2023Article
- A Novel Deep Learning Method Based on an Overlapping Time Window Strategy for Brain-Computer Interface-Based Stroke Rehabilitation.Brain sciences · 2022Article
- Improving Depressive Symptoms of Post-stroke Depression Using the Shugan Jieyu Capsule: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neurology · 2022Article
- The etiologies of post-stroke depression: Different between lacunar stroke and non-lacunar stroke.Clinics (Sao Paulo, Brazil) · 2022Article
- Neural Substrates of Poststroke Depression: Current Opinions and Methodology Trends.Frontiers in neuroscience · 2022Review
- Deep Brain Stimulation Modulates Multiple Abnormal Resting-State Network Connectivity in Patients With Parkinson's Disease.Frontiers in aging neuroscience · 2022Article
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8 authors.
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Abstract
Post stroke depression (PSD) is a serious complication of stroke. Brain imaging is an important method of studying the mechanism of PSD. However, few studies have focused on the single lesion location. The aim of this study was to investigate the brain mechanism of frontal lobe PSD using combined voxel-based morphometry (VBM) and functional magnetic resonance imaging (fMRI). In total, 30 first-time ischemic frontal lobe stroke patients underwent T1 weighted MRI and resting-state fMRI scans. Clinical assessments included the 24-item Hamilton Rating Scale for Depression, the National Institutes of Health Stroke Scale, and the Mini-Mental State Examination. In our result, decreased gray matter (GM) volume in patients was observed in the prefrontal cortex, limbic system and motor cortex. The anterior cingulate cortex, selected as a seed to perform connectivity analyses, showed a greatly decreased functional connectivity with the prefrontal cortex, cingulate cortex, and motor cortex, but had an increased functional connectivity with the hippocampus gyrus, parahippocampa gyrus, insular, and amygdala. Stroke lesion location reduces excitability of brain areas in the ipsilateral brain. PSD affects mood through the brain network of the prefrontal-limbic circuit. Some brain networks, including motor cortex and the default mode network, show other characteristics of PSD brain network.
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