Evidence map›Paper›PMID 29038450›Full record

Trial reportScientific reports2017

Visuo-acoustic stimulation that helps you to relax: A virtual reality setup for patients in the intensive care unit.

Stephan M Gerber, Marie-Madlen Jeitziner, Patric Wyss, Alvin Chesham, Prabitha Urwyler, René M Müri, Stephan M Jakob, Tobias Nef

2 registry-linked trialsOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 58 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03569358 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Safety, Tolerability, and Early Efficacy of Immersive Virtual Reality for Early Neurocognitive Stimulation in the Intensive Care Unit.

TypeinterventionalSponsorChangi General HospitalRan2018 to 2019Enrolled40ConditionsMechanical Ventilation, Virtual Reality, DeliriumArmsImmersive Virtual Reality, EEG headband
NCT04498585 nasuspendednot on this mapstarted 2021, after this paper: background citation

Virtual Reality Stimulation to Relax and Reduce the Incidence of Delirium

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2021 to 2023Enrolled920ConditionsDelirium, Cognitive ImpairmentArmsVR Stimulation
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 145 citations in OpenAlex.

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  17. Effect of Virtual Zen Garden on Quality of Life of Residents in Long-Term Care Home.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Stephan M GerberGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
Marie-Madlen JeitzinerDepartment of Intensive Care Medicine, University Hospital Bern (Inselspital), University of Bern, Bern, Switzerland.
Patric WyssGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
Alvin CheshamGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
Prabitha UrwylerGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
René M MüriGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland.
Stephan M JakobDepartment of Intensive Care Medicine, University Hospital Bern (Inselspital), University of Bern, Bern, Switzerland.
Tobias NefGerontechnology & Rehabilitation Group, University of Bern, Bern, Switzerland. tobias.nef@artorg.unibe.ch.
University of Bern · CHUniversity Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After prolonged stay in an intensive care unit (ICU) patients often complain about cognitive impairments that affect health-related quality of life after discharge. The aim of this proof-of-concept study was to test the feasibility and effects of controlled visual and acoustic stimulation in a virtual reality (VR) setup in the ICU. The VR setup consisted of a head-mounted display in combination with an eye tracker and sensors to assess vital signs. The stimulation consisted of videos featuring natural scenes and was tested in 37 healthy participants in the ICU. The VR stimulation led to a reduction of heart rate (p = 0. 049) and blood pressure (p = 0.044). Fixation/saccade ratio (p < 0.001) was increased when a visual target was presented superimposed on the videos (reduced search activity), reflecting enhanced visual processing. Overall, the VR stimulation had a relaxing effect as shown in vital markers of physical stress and participants explored less when attending the target. Our study indicates that VR stimulation in ICU settings is feasible and beneficial for critically ill patients.

Indexed as

Acoustic StimulationPhotic StimulationVirtual RealityAdultAgedAged, 80 and overCritical CareFeasibility StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedRelaxation TherapySurveys and QuestionnairesTime Factors

Identifiers

PMID29038450
PMCPMC5643433
OpenAlexW2762490179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.