Evidence map›Paper›PMID 29038382›Full record

ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2017

Protonation of carboxyl groups in EuDOTA-tetraamide complexes results in catalytic prototropic exchange and quenching of the CEST signal.

Lei Zhang, Osasere M Evbuomwan, Michael Tieu, Piyu Zhao, Andre F Martins, A Dean Sherry

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Lanthanide-Based TAngewandte Chemie (International ed. in English) · 2017
    Article
  3. Challenges for chemistry in molecular imaging.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei ZhangDepartment of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080, USA.
Osasere M EvbuomwanDepartment of chemistry and biochemistry, Gonzaga University, Spokane, WA 99258, USA.
Michael TieuDepartment of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080, USA.
Piyu ZhaoDepartment of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080, USA.
Andre F MartinsDepartment of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080, USA.ORCID http://orcid.org/0000-0002-0171-0261
A Dean SherryDepartment of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080, USA dean.sherry@utsouthwestern.edu.

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Sandi Leigh Pruitt · 2010 to 2026
$53.7M
TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
PARACEST AGENTS FOR MOLECULAR IMAGING OF CANCER BY MRIR01CA115531 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SHERRY, DEAN · 2005 to 2021
$4.2M
NCI NIH HHS P30 CA142543NCI NIH HHS R01 CA115531NIBIB NIH HHS P41 EB015908
6 · The paper itself

Abstract

The CEST properties of EuDOTA-tetraamide complexes bearing pendant carboxylate and carboxyl ethyl esters were measured as a function of pH. The CEST signal from the Eu

Indexed as

Eu complexMRI contrast agentpH sensor

Identifiers

PMID29038382
PMCPMC5647270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.