ArticlePhysiological reports2017
Tumor necrosis factor
Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Effect of Potassium-Magnesium Sulfate on Intestinal Dissociation and Absorption Rate, Immune Function, and Expression of NLRP3 Inflammasome, Aquaporins and Ion Channels in Weaned Piglets.Animals : an open access journal from MDPI · 2025Article
- Roles and regulation of Aquaporin-3 in maintaining the gut health: an updated review.Frontiers in physiology · 2023Review
- Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- dDAVP Downregulates the AQP3-Mediated Glycerol TransportFrontiers in cell and developmental biology · 2022Article
- A Functional Variant in the Aquaporin-3 Promoter Modulates Its Expression and Correlates With Resistance to Porcine Epidemic Virus Infection in Porcine Intestinal Epithelial Cells.Frontiers in microbiology · 2022Article
- Differential regulation of the water channel protein aquaporins in chondrocytes of human knee articular cartilage by aging.Scientific reports · 2021Article
- Novel Characterization of Constipation Phenotypes in ICR Mice Orally Administrated with Polystyrene Microplastics.International journal of molecular sciences · 2021Article
- Action Mode of Gut Motility, Fluid and Electrolyte Transport in Chronic Constipation.Frontiers in pharmacology · 2021Review
- High Levels of Tumor Necrosis Factor-Alpha Reduce Placental Aquaporin 3 Expression and ImpairFrontiers in physiology · 2021Article
- Role of Aquaporins in Inflammation-a Scientific Curation.Inflammation · 2020Review
- Maren Pills Improve Constipation via Regulating AQP3 and NF-Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Hypoxia-Induced Aquaporin-3 Changes Hepatocellular Carcinoma Cell Sensitivity to Sorafenib by Activating the PI3K/Akt Signaling Pathway.Cancer management and research · 2020Article
- Bioinformatics Unmasks the Maneuverers of Pain Pathways in Acute Kidney Injury.Scientific reports · 2019Article
- Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro.Scientific reports · 2019Article
- Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Interferon gamma decreases intestinal epithelial aquaporin 3 expression through downregulation of constitutive transcription.Journal of molecular medicine (Berlin, Germany) · 2018Article
- Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon.Journal of natural medicines · 2018Article
- New Perspectives on the Potential Role of Aquaporins (AQPs) in the Physiology of Inflammation.Frontiers in physiology · 2018Review
- Tumor necrosis factorPhysiological reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory diseases of the gut are associated with altered electrolyte and water transport, leading to the development of diarrhea. Epithelially expressed aquaporins (AQPs) are downregulated in inflammation, although the mechanisms involved are not known. We hypothesized that AQP3 expression in intestinal epithelial cells is altered in intestinal inflammation and that these changes are driven by tumor necrosis factor (TNF)
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.