Evidence map›Paper›PMID 29038352›Full record

ArticlePhysiological reports2017

Differential relationships of hepatic and epicardial fat to body composition in HIV.

Lindsay T Fourman, Michael T Lu, Hang Lee, Kathleen V Fitch, Travis R Hallett, Jakob Park, Natalia Czerwonka, Julian Weiss, Takara L Stanley, Janet Lo and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Approach to the Patient With Lipodystrophy.The Journal of clinical endocrinology and metabolism · 2022
    Article
  4. HIV and antiretroviral therapy-related fat alterations.Nature reviews. Disease primers · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lindsay T FourmanDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Michael T LuDepartment of Radiology, Cardiac PET MR CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Hang LeeMGH Biostatistics Center, Massachusetts General Hospital, Boston, Massachusetts.
Kathleen V FitchDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Travis R HallettDepartment of Radiology, Cardiac PET MR CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.ORCID http://orcid.org/0000-0001-7571-5148
Jakob ParkDepartment of Radiology, Cardiac PET MR CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Natalia CzerwonkaDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Julian WeissDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Takara L StanleyDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Janet LoDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Steven K GrinspoonDepartment of Medicine, Endocrine Division, Program in Nutritional Metabolism, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts sgrinspoon@mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

ZD6416 Analgesic--Painful Distal Symmetrical PolyneuropaM01RR001066 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, EMERY N · 1985 to 2008
$37.4M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTOPHER P DUGGAN · 1994 to 2026
$31.6M
TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
GASTROINTESTINAL DISEASE TRAINING GRANTT32DK007038 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI COLGAN, SEAN P · 1986 to 2020
$3.5M
Atherosclerosis and Inflammation in HIV DiseaseK23HL092792 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LO, JANET · 2008 to 2012
$705k
Subclinical Coronary Atherosclerosis in HIV-Infected PatientsF32HL088991 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LO, JANET · 2007 to 2007
$12k
NCRR NIH HHS M01 RR001066NHLBI NIH HHS F32 HL088991NHLBI NIH HHS K23 HL092792NIDDK NIH HHS P30 DK040561NIDDK NIH HHS T32 DK007028NIDDK NIH HHS T32 DK007038
6 · The paper itself

Abstract

HIV-infected patients commonly experience changes in central and peripheral fat content as well as ectopic fat accumulation. However, whether hepatic and epicardial fat stores relate differentially to body composition or how these associations are modified by HIV status has not been well explored. A previously recruited sample of 124 HIV-infected patients and 58 healthy controls had undergone dual energy X-ray absorptiometry (DEXA) and computed tomography (CT) from which body composition measures, liver-spleen ratio, and epicardial fat volume were obtained. Unique to the HIV-infected group, there was a parabolic association between abdominal subcutaneous adipose tissue (SAT) area and liver-spleen ratio (

Indexed as

AdiposityAdultCase-Control StudiesFemaleHeartHIV InfectionsHumansLiverMaleMiddle AgedSpleenEctopic fatEpicardial fatNonalcoholic fatty liver disease (NAFLD)Subcutaneous adipose tissueVisceral adipose tissue

Identifiers

PMID29038352
PMCPMC5641927
OpenAlexW2765262531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.