Evidence map›Paper›PMID 29038295›Full record

ArticleThe Journal of biological chemistry2017

Characterization of aromatic residue-controlled protein retention in the endoplasmic reticulum of

Meng Mei, Chao Zhai, Xinzhi Li, Yu Zhou, Wenfang Peng, Lixin Ma, Qinhong Wang, Brent L Iverson, Guimin Zhang, Li Yi

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Functional Characterization ofInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Metabolic Engineering ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The Function of KDEL Receptors as UPR Genes in Disease.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Interactions by Disorder - A Matter of Context.Frontiers in molecular biosciences · 2020
    Review
  17. Article
  18. Extracellular esterase activity as an indicator of endoplasmic reticulum calcium depletion.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Meng MeiFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Chao ZhaiFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Xinzhi LiFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Yu ZhouFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Wenfang PengFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Lixin MaFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China.
Qinhong Wangthe Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China, and.
Brent L Iversonthe Department of Chemistry, University of Texas, Austin, Texas 78712.
Guimin ZhangFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China, zhangguimin6@hotmail.com.
Li YiFrom the Hubei Collaborative Innovation Center for Green Transformation of Bioresources, Hubei Key Laboratory of Industrial Biotechnology, Hubei University, Wuhan 430062, China, liyi@hubu.edu.cn.ORCID 0000-0002-7835-6985
Hubei University · CNChinese Academy of Sciences · CNThe University of Texas at Austin · US

Funding

Mediating and Moderating Effects of Fetal Alcohol-Related Iron Deficiency in FASDR21AA022203 · NIAAA · WAYNE STATE UNIVERSITY · PI CARTER, ROBERT COLIN, JACOBSON, SANDRA W. · 2014 to 2015
$405k
NIAAA NIH HHS R21 AA022203
6 · The paper itself

Abstract

An endoplasmic reticulum (ER) retention sequence (ERS) is a characteristic short sequence that mediates protein retention in the ER of eukaryotic cells. However, little is known about the detailed molecular mechanism involved in ERS-mediated protein ER retention. Using a new surface display-based fluorescence technique that effectively quantifies ERS-promoted protein ER retention within

Indexed as

Models, MolecularAmino Acid MotifsAmino Acids, AromaticAmino Acid SubstitutionCell LineEndoplasmic ReticulumHumansMembrane ProteinsMolecular WeightMutagenesis, Site-DirectedMutationProtein ConformationProtein EngineeringProtein Interaction Domains and MotifsReceptors, Cytoplasmic and NuclearReceptors, PeptideAmino Acids, AromaticERD1 protein, S cerevisiaeERD2 protein, S cerevisiaeERS1 protein, S cerevisiaeHDEL receptorKDEL receptorMembrane ProteinsReceptors, Cytoplasmic and NuclearReceptors, PeptideRecombinant Fusion ProteinsSaccharomyces cerevisiae Proteinsendoplasmic reticulum (ER)Erd2ER retention sequenceflow cytometryfluorescenceprotein ER retentionprotein sortingprotein trafficking (Golgi)surface displayyeast

Identifiers

PMID29038295
PMCPMC5733606
OpenAlexW2765541150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.