ArticleJournal of bacteriology2018
The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensis.
Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- Translation as a regulatory hub for secondary metabolism in Streptomyces spp.Essays in biochemistry · 2026Review
- Expanding perspectives on specialized metabolism in Streptomyces bacteria.Essays in biochemistry · 2026Review
- Dual-calibration RT-qPCR reveals distinct dnaK1/2/3 and groEL1/2 expression dynamics under heat and acid stress in the sinefungin producer Streptomyces incarnatus.Scientific reports · 2026Article
- Recent advances in lincosamide biosynthetic studies.The Journal of antibiotics · 2026Review
- Chromosome-level genome assembly and annotation of a novel potato common scab pathogen.Frontiers in plant science · 2026Article
- Marine-derived L-asparaginase: unlocking marine power in anti-tumor therapeutics.Frontiers in immunology · 2025Review
- TetR family regulator AbrT controls lincomycin production and morphological development in Streptomyces lincolnensis.Microbial cell factories · 2024Article
- Coupled strategy based on regulator manipulation and medium optimization empowers the biosynthetic overproduction of lincomycin.Synthetic and systems biotechnology · 2024Article
- Three new LmbU targets outside lmb cluster inhibit lincomycin biosynthesis in Streptomyces lincolnensis.Microbial cell factories · 2024Article
- PAS domain containing regulator SLCG_7083 involved in morphological development and glucose utilization in Streptomyces lincolnensis.Microbial cell factories · 2023Article
- LcbR1, a newly identified GntR family regulator, represses lincomycin biosynthesis in Streptomyces lincolnensis.Applied microbiology and biotechnology · 2023Article
- AflQ1-Q2 represses lincomycin biosynthesis via multiple cascades in Streptomyces lincolnensis.Applied microbiology and biotechnology · 2023Article
- Inducing Global Expression of Actinobacterial Biosynthetic Gene Clusters.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Article
- GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery.Nature communications · 2020Article
- Coordinated regulation for nature products discovery and overproduction inSynthetic and systems biotechnology · 2020Article
- Complete genome sequence of high-yield strainSynthetic and systems biotechnology · 2020Article
- Comparative transcriptomic analysis reveals the significant pleiotropic regulatory effects of LmbU on lincomycin biosynthesis.Microbial cell factories · 2020Article
- sRNA EsrE Is Transcriptionally Regulated by the Ferric Uptake Regulator Fur inJournal of microbiology and biotechnology · 2020Article
- TetR-Type Regulator SLCG_2919 Is a Negative Regulator of Lincomycin Biosynthesis in Streptomyces lincolnensis.Applied and environmental microbiology · 2019Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lincomycin A is a clinically important antimicrobial agent produced by
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.