Evidence map›Paper›PMID 29038251›Full record

ArticleJournal of bacteriology2018

Stress Introduction Rate Alters the Benefit of AcrAB-TolC Efflux Pumps.

Ariel M Langevin, Mary J Dunlop

Abstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Role of Efflux Pumps on Antimicrobial Resistance inInternational journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Microscopic Approach to Intrinsic Antibiotic Resistance.The journal of physical chemistry. B · 2021
    Article
  10. Article
  11. Article
  12. TolCV1 Has Multifaceted Roles DuringFrontiers in cellular and infection microbiology · 2021
    Article
  13. Overexpression ofFrontiers in microbiology · 2021
    Article
  14. Article
  15. Article
  16. High production of triterpenoids inBiotechnology for biofuels · 2020
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ariel M LangevinDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA.
Mary J DunlopDepartment of Biomedical Engineering, Boston University, Boston, Massachusetts, USA mjdunlop@bu.edu.

Funding

Feedback and Noise in a Multiple Antibiotic Resistance CircuitR01AI102922 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Mary J. Dunlop · 2014 to 2026
$4.7M
NIAID NIH HHS R01 AI102922
6 · The paper itself

Abstract

Stress tolerance studies are typically conducted in an all-or-none fashion. However, in realistic settings-such as in clinical or metabolic engineering applications-cells may encounter stresses at different rates. Therefore, how cells tolerate stress may depend on its rate of appearance. To address this, we studied how the rate of stress introduction affects bacterial stress tolerance by focusing on a key stress response mechanism. Efflux pumps, such as AcrAB-TolC of

Indexed as

Stress, PhysiologicalAnti-Bacterial AgentsBiofuelsCarrier ProteinsChloramphenicolEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMembrane Transport ProteinsMicrobial Sensitivity TestsModels, TheoreticalAcrAB-TolC protein, E coliAnti-Bacterial AgentsBiofuelsCarrier ProteinsChloramphenicolEscherichia coli ProteinsMembrane Transport Proteinsantibioticsbiofuelsdynamic environmentefflux pumpsstress tolerance

Identifiers

PMID29038251
PMCPMC5717160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.