ReviewCold Spring Harbor perspectives in biology2018
Interplay between Microbes and the Circadian Clock.
Review in Cold Spring Harbor perspectives in biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Artificial Light at Night Consistently Impacts Avian Physiology and Behaviour: A Meta-Analysis.Ecology letters · 2026Pooled it
- Effects of LED Light Colors on the Growth Performance, Intestinal Morphology, Cecal Short-Chain Fatty Acid Concentrations and Microbiota in Broilers.Animals : an open access journal from MDPI · 2023Article
- Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping.International journal of molecular sciences · 2023Review
- Brain histone beta-hydroxybutyrylation couples metabolism with gene expression.Cellular and molecular life sciences : CMLS · 2023Article
- Biological Clock and Inflammatory Bowel Disease Review: From the Standpoint of the Intestinal Barrier.Gastroenterology research and practice · 2022Review
- Circadian Rhythms, Disease and Chronotherapy.Journal of biological rhythms · 2021Review
- Article
- Time-resolved transcriptional profiling of Trichinella-infected murine myocytes helps to elucidate host-pathogen interactions in the muscle stage.Parasites & vectors · 2021Article
- Dietary Conjugated Linoleic Acid Modulates the Hepatic Circadian Clock ProgramFrontiers in nutrition · 2021Article
- Reshaping circadian metabolism in the suprachiasmatic nucleus and prefrontal cortex by nutritional challenge.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Review
- Circadian Regulation of the Biology of Allergic Disease: Clock Disruption Can Promote Allergy.Frontiers in immunology · 2020Review
- Microbiome diurnal rhythmicity and its impact on host physiology and disease risk.EMBO reports · 2019Review
- The Circadian Clock as an Essential Molecular Link Between Host Physiology and Microorganisms.Frontiers in cellular and infection microbiology · 2019Review
- Circadian rhythms in the pathogenesis of gastrointestinal diseases.World journal of gastroenterology · 2018Article
- Inflammaging: a new immune-metabolic viewpoint for age-related diseases.Nature reviews. Endocrinology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Circadian rhythms influence virtually all life forms on our planet, a notion that opens the question on how the circadian cycles of individual organisms may interplay with each other. In mammals, a potentially dangerous environmental stress is represented by encounters with infectious agents. Microbial attack is a major risk for organismal homeostasis and therefore needs to be efficiently counteracted by mechanisms implemented by the host immune system. Accumulating evidence shows that the immune system may anticipate an emerging pathogenic exposure through an enhanced inflammatory state. Notably, the circadian clock orchestrates these anticipatory responses to fluctuating conditions in the external world. In this article, we review the current knowledge about the relationship between the circadian clock and pathogenic infections. We discuss the role of the circadian clock against infection and specific pathogens, the core clock proteins involved in the defense mechanisms, and the specific tissue or cell type in which they function to counteract the infection. Finally, circadian oscillations in the gut microbiome composition and its possible role in protecting against foodborne pathogen colonization are presented.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.