ArticleAmerican journal of ophthalmology2017
Peripheral Visual Fields in ABCA4 Stargardt Disease and Correlation With Disease Extent on Ultra-widefield Fundus Autofluorescence.
Article in American journal of ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Clinical application of ultra-widefield fundus autofluorescence.International ophthalmology · 2021Pooled it
- Full-Field Stimulus Threshold: A Key Functional Outcome Measure in Retinal Diseases and Clinical Trials.Journal of clinical medicine · 2026Review
- Comparative analysis of generic vision-language models in detecting and diagnosing inherited retinal diseases using fundus photographs.Eye (London, England) · 2025Article
- Retinoid dynamics in vision: from visual cycle biology to retina disease treatments.Pharmacology & therapeutics · 2025Review
- Retinal Imaging Findings in Inherited Retinal Diseases.Journal of clinical medicine · 2024Review
- Prognostication in Stargardt Disease Using Fundus Autofluorescence: Improving Patient Care.Ophthalmology · 2023Article
- Stargardt disease: Multimodal imaging: A review.Clinical & experimental ophthalmology · 2021Review
- Atrophy Expansion Rates in Stargardt Disease Using Ultra-Widefield Fundus Autofluorescence.Ophthalmology science · 2021Article
- Evidence of complement dysregulation in outer retina of Stargardt disease donor eyes.Redox biology · 2020Article
- Reviewing the Role of Ultra-Widefield Imaging in Inherited Retinal Dystrophies.Ophthalmology and therapy · 2020Review
- Wide-field fundus autofluorescence imaging in patients with hereditary retinal degeneration: a literature review.International journal of retina and vitreous · 2019Review
- Ultra-widefield retinal imaging: an update on recent advances.Therapeutic advances in ophthalmologyReview
- The role of multimodal imaging and vision function testing inTherapeutic advances in ophthalmologyReview
- Wide field imaging biomarkers: A different perspective.Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4 Stargardt disease (STGD) and correlate these data with functional outcome measures.
designRetrospective cross-sectional study.
methodsSetting: Kellogg Eye Center, University of Michigan. STUDY POPULATION: Sixty-five patients with clinical diagnosis and proven pathogenic variants in the ABCA4 gene. Observational Procedures: The UWF-FAF images were obtained using Optos (200 degrees) and classified into 3 types. Functional testing included kinetic widefield perimetry, full-field electroretinogram (ffERG), and visual acuity (VA). All results were evaluated with respect to UWF-FAF classification.
main outcome measuresClassification of UWF-FAF; area comprising the I4e, III4e, and IV4e isopters; ffERG patterns; and VA.
resultsFor UWF-FAF, 27 subjects (41.5%) were classified as type I, 17 (26.2%) as type II, and 21 (32.4%) as type III. The area of each isopter correlated inversely with the extent of the disease and all isopters were able to detect differences among UWF-FAF types (IV4e, P = .0013; III4e, P = .0003; I4e, P < .0001 = 3.93e
conclusionPatients with widespread disease presented with more constriction of peripheral visual fields and had more dysfunction on ffERG and worse VA compared to patients with disease confined to the macula. UWF-FAF images may provide information for estimating peripheral and central visual function in STGD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.