ReviewTrends in genetics : TIG2018
Caenorhabditis elegans Dosage Compensation: Insights into Condensin-Mediated Gene Regulation.
Review in Trends in genetics : TIG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 44 citations in OpenAlex.
- Establishment and Maintenance of Repressed Chromatin States on Dosage-Compensated Sex Chromosomes.Biomolecules · 2026Review
- Parallel Evolution of X Chromosome-Specific Structural Maintenance of Chromosomes Complexes in Two Nematode Lineages.Molecular biology and evolution · 2025Article
- Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana.PLoS genetics · 2025Article
- Cohesin organizes 3D DNA contacts surrounding active enhancers inGenome research · 2025Article
- Human XIST: Origin and Divergence of aNon-coding RNA · 2025Review
- Structural Maintenance of Chromosomes Complexes.Methods in molecular biology (Clifton, N.J.) · 2025Review
- Cohesin organizes 3D DNA contacts surrounding active enhancers inbioRxiv : the preprint server for biology · 2024Article
- Condensin I folds the Caenorhabditis elegans genome.Nature genetics · 2024Article
- Analysis of developmental gene expression using smFISH andbioRxiv : the preprint server for biology · 2024Article
- Function and Evolution of the Loop Extrusion Machinery in Animals.International journal of molecular sciences · 2023Review
- Article
- Increased gene dosage and mRNA expression from chromosomal duplications in Caenorhabditis elegans.G3 (Bethesda, Md.) · 2022Article
- Dual roles for nuclear RNAi Argonautes in Caenorhabditis elegans dosage compensation.Genetics · 2022Article
- The histone H4 lysine 20 demethylase DPY-21 regulates the dynamics of condensin DC binding.Journal of cell science · 2022Article
- Review
- Hatched and starved: Two chromatin compaction mechanisms join forces to silence germ cell genome.The Journal of cell biology · 2021Article
- A role for condensin in mediating transcriptional adaptation to environmental stimuli.Life science alliance · 2021Article
- A Role forCells · 2020Article
- Difference in phenotypic severity of presumed null alleles ofmicroPublication biology · 2020Article
- Emerging Roles for Chromo Domain Proteins in Genome Organization and Cell Fate inFrontiers in cell and developmental biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Recent work demonstrating the role of chromosome organization in transcriptional regulation has sparked substantial interest in the molecular mechanisms that control chromosome structure. Condensin, an evolutionarily conserved multisubunit protein complex, is essential for chromosome condensation during cell division and functions in regulating gene expression during interphase. In Caenorhabditis elegans, a specialized condensin forms the core of the dosage compensation complex (DCC), which specifically binds to and represses transcription from the hermaphrodite X chromosomes. DCC serves as a clear paradigm for addressing how condensins target large chromosomal domains and how they function to regulate chromosome structure and transcription. Here, we discuss recent research on C. elegans DCC in the context of canonical condensin mechanisms as have been studied in various organisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.