Evidence map›Paper›PMID 29037181›Full record

Trial reportBMC pregnancy and childbirth2017

The MOVE-trial: Monocryl® vs. Vicryl Rapide™ for skin repair in mediolateral episiotomies: a randomized controlled trial.

Roeland Odijk, Bernadette Hennipman, Melek Rousian, Khadija Madani, Marja Dijksterhuis, Jan Willem de Leeuw, Arjan van Hof

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC pregnancy and childbirth, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roeland OdijkDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands. RGDOdijk@gmail.com.
Bernadette HennipmanDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.
Melek RousianDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.
Khadija MadaniDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.
Marja DijksterhuisDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.
Jan Willem de LeeuwDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.
Arjan van HofDepartment of Obstetrics and Gynecology, Ikazia Hospital, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that complaints after episiotomy repair depend on the method and material used for repair. The objective of our study was to determine which of two frequently used suture materials, Monocryl® (poliglecaprone 25) and Vicryl Rapide™ (polyglactin 910), is superior for intracutaneous closure of the skin in mediolateral episiotomies.

methodsIn a randomized controlled trial performed in a teaching hospital in the Netherlands between 2010 and 2013 250 primiparous women with uncomplicated mediolateral episiotomies were randomly allocated to intracutaneous skin closure with either Monocryl® or Vicryl Rapide™. All other layers were sutured with Vicryl 2-0 and Vicryl 0 in both groups. Pain scores and complications were documented using questionnaires during the first three months post partum. The primary outcome was pain 10 days after delivery in sitting position established by Visual Analogous Scale (VAS). Secondary outcomes were pain scores at different time points and reported complications such as infections, dehiscence and dyspareunia one day, 10 days, six weeks and three months after delivery.

resultsOf 250 allocated women 54% returned questionnaires. No statistical difference was found between both groups for the primary outcome (VAS 2,8 (95% CI 2,18-3,44) vs. VAS 2,5 (95% CI 2,00-2,98), p = 0,43). With regard to secondary outcomes only self-reported dehiscence was significantly different, favouring Monocryl® (10% vs. 25%, p = 0.016).

conclusionsUse of Monocryl® 3-0 and Vicryl Rapide™ 3-0 for intracutaneous closure of the skin after mediolateral episiotomy leads to equal pain scores ten days after delivery and therefore both materials may be considered for this use. Monocryl® 3-0 might be favourable over Vicryl Rapide™ 3-0 due to less self-reported dehiscence after intracutaneous closure of the skin in mediolateral episiotomies.

trial registrationThe trial was retrospectively registered under trial nr. ISRCTN29869308 on 20-04-2016.

Indexed as

SuturesSuture TechniquesAdultDioxanesDyspareuniaEpisiotomyFemaleHumansNetherlandsPerineumPolyestersPolyglactin 910Postoperative ComplicationsPregnancySurgical Wound DehiscenceSurgical Wound InfectionDioxanesglycolide E-caprolactone copolymerPolyestersPolyglactin 910Episiotomy; randomized controlled trial; polyglactin 910PainPoliglecaprone 25Wound dehiscence

Identifiers

PMID29037181
PMCPMC5644141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.