ArticleBMC plant biology2017
TaFlo2-A1, an ortholog of rice Flo2, is associated with thousand grain weight in bread wheat (Triticum aestivum L.).
Article in BMC plant biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identification of quantitative trait loci (QTL) and meta-QTL analysis for kernel size-related traits in wheat (Triticum aestivum L.).BMC plant biology · 2022Pooled it
- Large-scale identification and association analysis of wheat grain weight genes using rice orthologs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome-wide association study identifies QTL and candidate genes for grain size and weight in a Triticum turgidum collection.The plant genome · 2025Article
- A novel variation ofMolecular breeding : new strategies in plant improvement · 2024Article
- A high-resolution genotype-phenotype map identifies the TaSPL17 controlling grain number and size in wheat.Genome biology · 2023Article
- Genomics for Yield and Yield Components in Durum Wheat.Plants (Basel, Switzerland) · 2023Review
- Meta-QTLs, ortho-meta QTLs and related candidate genes for yield and its component traits under water stress in wheat (Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- The double round-robin population unravels the genetic architecture of grain size in barley.Journal of experimental botany · 2022Article
- Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- A superior allele of the wheat gene TaGL3.3-5B, selected in the breeding process, contributes to seed size and weight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- GWAS and RNA-seq analysis uncover candidate genes associated with alkaline stress tolerance in maize (Frontiers in plant science · 2022Article
- Genome-wide association study of yield-related traits in common wheat (Frontiers in plant science · 2022Article
- Quantitative trait loci identification and breeding value estimation of grain weight-related traits based on a new wheat 50K single nucleotide polymorphism array-derived genetic map.Frontiers in plant science · 2022Article
- Article
- Ectopic expression of TaBG1 increases seed size and alters nutritional characteristics of the grain in wheat but does not lead to increased yields.BMC plant biology · 2021Article
- Fine mapping and validation of a major QTL for grain weight on chromosome 5B in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Dissection of Genetic Basis Underpinning Kernel Weight-Related Traits in Common Wheat.Plants (Basel, Switzerland) · 2021Article
- QTL Mapping and Validation for Kernel Area and Circumference in Common WheatFrontiers in plant science · 2021Article
- Genome-Wide Association Study and Post-genome-Wide Association Study Analysis for Spike Fertility and Yield Related Traits in Bread Wheat.Frontiers in plant science · 2021Article
- Identification and validation of quantitative trait loci for kernel traits in common wheat (Triticum aestivum L.).BMC plant biology · 2020Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Flo2 gene is a member of a conserved gene family in plants. This gene has been found to be related to thousand grain weight (TGW) in rice. Its orthologs in hexaploid wheat were cloned, and the haplotype variation in TaFlo2-A1 was tested for association with TGW.
resultsThe cloned sequences of TaFlo2-A1, TaFlo2-B1 and TaFlo2-D1 contained 23, 23 and 24 exons, respectively. The deduced proteins of TaFlo2-A1 (1734 aa), TaFlo2-B1 (1698 aa) and TaFlo2-D1 (1682 aa) were highly similar (>94%) and exhibited >77% similarity with the rice FLO2 protein. Like the rice FLO2 protein, four tetratricopeptide repeat (TPR) motifs were observed in the deduced TaFLO2 protein. An 8-bp InDel (-10 to -17 bp) in the promoter region and five SNPs in first intron of TaFlo2-A1 together formed two haplotypes, TaFlo2-A1a and TaFlo2-A1b, in bread wheat. TaFlo2 was located on homeologous group 2 chromosomes. TaFlo2-A1 was inferred to be located on deletion bin '2AL1-0.85-1.00'. The TaFlo2-A1 haplotypes were characterized in the Chinese Micro Core Collection (MCC) and Pakistani wheat collection using the molecular marker TaFlo2-Indel8. TaFlo2-A1 was found to be associated with TGW but not with grain number per spike (GpS) in both the MCC and Pakistani wheat collections. The frequency of TaFlo2-A1b (positive haplotype) was low in commercial wheat cultivars; thus this haplotype can be selected to improve grain weight without negatively affecting GpS. The expression level of TaFlo2-A1 in developing grains at 5 DAF (days after flowering) was positively correlated with TGW in cultivars carrying the positive haplotype.
conclusionThis study will likely lead to additional investigations to understand the regulatory mechanism of the Flo2 gene in hexaploid wheat. Furthermore, the newly developed molecular marker 'TaFlo2-InDel8' could be incorporated into the kit of wheat breeders for use in marker-assisted selection.
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