Evidence map›Paper›PMID 29036928›Full record

ArticleInternational journal of molecular sciences2017

Plasma miR-155, miR-203, and miR-205 are Biomarkers for Monitoring of Primary Cutaneous T-Cell Lymphomas.

Nina Dusílková, Petra Bašová, Jindřich Polívka, Ondřej Kodet, Vojtěch Kulvait, Michal Pešta, Marek Trněný, Tomáš Stopka

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Clinical Guidelines and New Molecular Targets for Cutaneous Lymphomas.International journal of molecular sciences · 2021
    Review
  11. Diagnosis of Early Mycosis Fungoides.Diagnostics (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nina DusílkováBIOCEV, First Faculty of Medicine, Charles University, 25250 Vestec, Czech Republic. nina.dusilkova@lf1.cuni.cz.
Petra BašováBIOCEV, First Faculty of Medicine, Charles University, 25250 Vestec, Czech Republic. basova.petra@gmail.com.
Jindřich PolívkaDepartment of Haematology, First Faculty of Medicine, Charles University and General Hospital, 12808 Prague, Czech Republic. jinpol@gmail.com.
Ondřej KodetBIOCEV, First Faculty of Medicine, Charles University, 25250 Vestec, Czech Republic. ondrej.kodet@lf1.cuni.cz.
Vojtěch KulvaitBIOCEV, First Faculty of Medicine, Charles University, 25250 Vestec, Czech Republic. kulvait@gmail.com.
Michal PeštaFaculty of Mathematics and Physics, Charles University, 18675 Prague, Czech Republic. pesta@karlin.mff.cuni.cz.
Marek TrněnýDepartment of Haematology, First Faculty of Medicine, Charles University and General Hospital, 12808 Prague, Czech Republic. trneny@cesnet.cz.
Tomáš StopkaBIOCEV, First Faculty of Medicine, Charles University, 25250 Vestec, Czech Republic. tstopka@lf1.cuni.cz.ORCID 0000-0001-7236-6894
Charles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cutaneous T-cell lymphomas (CTCL) affect the skin and tend to transform and spread. CTCL involves primarily the Mycosis fungoides (MF) and more aggressive Sezary syndrome (SS). Oncogenic microRNAs (miRs) are stable epigenetic inhibitors often deregulated in the tumour and detectable as biomarkers in non-cellular fractions of peripheral blood. The tumour-specific expression of miR-155, miR-203, and miR-205 was shown to correctly diagnose CTCL. We herein asked whether these microRNAs can be used as plasma biomarkers for clinical CTCL monitoring. Patients with CTCL (

Indexed as

Biomarkers, TumorCirculating MicroRNAAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsCase-Control StudiesFemaleGene Expression ProfilingHumansLiquid BiopsyLymphoma, T-Cell, CutaneousMaleMicroRNAsMiddle AgedNeoplasm StagingPrognosisBiomarkers, TumorCirculating MicroRNAMicroRNAsMIR205, humanMIRN155 microRNA, humanMIRN203 microRNA, humanatopic dermatitiscutaneous T-cell lymphomas (CTCL)microRNAmycosis fungoidesPsoriasis vulgarisSezary syndrome

Identifiers

PMID29036928
PMCPMC5666818
OpenAlexW2761666143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.