Evidence map›Paper›PMID 29036741›Full record

ReviewSeminars in reproductive medicine2017

The Effects of Aspirin in Gestation and Reproduction (EAGeR) Trial: A Story of Discovery.

Matthew T Connell, Lindsey A Sjaarda, Rose G Radin, Daniel Kuhr, Sunni L Mumford, Torie C Plowden, Robert M Silver, Enrique F Schisterman

Abstract readReview
In one paragraph

Review in Seminars in reproductive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Antiplatelet agents for preventing pre-eclampsia and its complications.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Article
  4. Article
  5. Eager to improve women's cardiovascular health.Paediatric and perinatal epidemiology · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew T ConnellDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Lindsey A SjaardaDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Rose G RadinDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Daniel KuhrDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Sunni L MumfordDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Torie C PlowdenDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Robert M SilverDepartment of Obstetrics and Gynecology, University of Utah and Intermountain Healthcare, Salt Lake City, Utah.
Enrique F SchistermanDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

Funding

EAGeR Trial - The Effects of Aspirin in Gestation and Reproduction TrialZIAHD008795 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PERKINS, NEIL · 2009 to 2025
$9.6M
EAGeR Trial - The Effects of Aspirin in Gestation and Reproduction TrialZ01HD008795 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SCHISTERMAN, ENRIQUE · 2007 to 2008
$596k
Phytoestrogens and Time to PregnancyZ01HD008796 · NICHD · CHILD HEALTH AND HUMAN DEVELOPMENT · PI SCHISTERMAN, ENRIQUE · 2007 to 2007
$3k
Intramural NIH HHS Z01 HD008795Intramural NIH HHS Z01 HD008796Intramural NIH HHS ZIA HD008795
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pregnancy RateAdolescentAdultAspirinC-Reactive ProteinFemaleHumansPregnancyPregnancy ComplicationsPremature BirthRandomized Controlled Trials as TopicReproductionYoung AdultAspirinC-Reactive Protein

Identifiers

PMID29036741
PMCPMC6234510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.